Characterisation of genes encoding for extended spectrum β-lactamase in Gram-negative bacteria causing healthcare-associated infections in Mwanza, Tanzania (Record no. 28013)
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| fixed length control field | 02353nam a22003137a 4500 |
| 001 - CONTROL NUMBER | |
| control field | 20240610111235.0 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | 20240610111235.0 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240610112111.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240610b |||||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | ddc |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Fuller form of name | Jenipher G. Mwakyabala |
| 245 ## - TITLE STATEMENT | |
| Title | Characterisation of genes encoding for extended spectrum β-lactamase in Gram-negative bacteria causing healthcare-associated infections in Mwanza, Tanzania |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania : |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences [CUHAS-Bugando] : |
| Date of publication, distribution, etc. | 2023 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | Includes References |
| 490 ## - SERIES STATEMENT | |
| Volume/sequential designation | African Journal of Laboratory MedicineVol. 12, No. 1 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract : <br/><br/>Healthcare-associated infections (HCAIs) caused by extended spectrum β-lactamase-producing Gram-negative bacteria (ESBL-GNB) increase morbidity and mortality. This cross-sectional study characterised ESBL genes (blaCTX-M, blaTEM and blaSHV) among 30 ceftriaxone-resistant GNB causing HCAIs between January 2022 and July 2022 by multiplex polymerase chain reaction assay at the zonal referral hospital in Mwanza, Tanzania. Twenty-five (83.3%) had at least one ESBL gene, of which 23/25 (92.0%) carried the blaCTX-M gene. Seventy-two percent (18/25) of the GNB-ESBL isolates carried more than one ESBL gene, of which the majority (88.8%; n = 16/25) carried the blaCTX-M and blaTEM genes. Extended spectrum β-lactamase genes, particularly blaCTX-M, are common among ceftriaxone-resistant GNB causing HCAIs.<br/><br/>What This Study Adds :This study revealed the distribution of genes (blaCTX-M, blaTEM and blaSHV) coding for ESBL production among ceftriaxone resistant GNB causing HCAIs However, all ESBL producing GNB were susceptible towards ceftriaxone-sulbactam indicating that ceftriaxone-sulbactam may be empirically prescribed for treating patients with HCAIs.<br/> |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | beta lactamases |
| General subdivision | extended spectrum beta-lactamase |
| General subdivision | Gram-negative bacteria |
| General subdivision | healthcare-associated infections |
| General subdivision | multiplex PCR assay |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Fuller form of name | Conjester I. Mtemisika |
| Fuller form of name | Stacy Mshana |
| Fuller form of name | Adam A. Mwakyoma |
| Fuller form of name | Vitus Silago |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://hdl.handle.net/10520/ejc-ajlab_v12_n1_a2107">https://hdl.handle.net/10520/ejc-ajlab_v12_n1_a2107</a> |
| Link text | https://hdl.handle.net/10520/ejc-ajlab_v12_n1_a2107 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | RESEARCH ARTICLES |
| Suppress in OPAC | |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
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| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 06/10/2024 | 20240610111235.0 | 06/10/2024 | 06/10/2024 | RESEARCH ARTICLES |