Low CD4 Counts and History of Sore Throat Predict High SARS-CoV-2 Seropositivity among Human Immunodeficiency Virus-Infected Patients in Mwanza, Tanzania. (Record no. 27994)
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| fixed length control field | 03331nam a22003857a 4500 |
| 001 - CONTROL NUMBER | |
| control field | 20240607202457.0 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | 20240607202457.0 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240607203327.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240607b |||||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | EISSN 2673-8112 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | ddc |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Fuller form of name | Helmut A. Nyawale |
| 245 ## - TITLE STATEMENT | |
| Title | Low CD4 Counts and History of Sore Throat Predict High SARS-CoV-2 Seropositivity among Human Immunodeficiency Virus-Infected Patients in Mwanza, Tanzania. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania : |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences [CUHAS-Bugando] : |
| Date of publication, distribution, etc. | 2023 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | Pages 01-10 |
| Extent | Includes References |
| 490 ## - SERIES STATEMENT | |
| Volume/sequential designation | COVID 2023, 3(4), 418-427; |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract :<br/><br/>Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic. Despite the fact that it affects all ages and profiles, some evidence shows that patients with comorbidities, including diabetes, obesity, and hypertension, are likely to be most affected. For chronic diseases, such as human immunodeficiency virus (HIV), information is scarce, with a few studies from high-income countries. This study reports predictors of SARS-CoV-2 seropositivity (IgG + IgM) among unvaccinated people living with HIV attending Bugando Medical Centre in Mwanza, Tanzania. <br/><br/>Methodology: A cross-sectional, hospital-based study involving 150 HIV-infected patients was conducted at Bugando Medical Centre between June and July 2022. A pretested questionnaire was used to collect the participants’ information. Blood samples were collected and used for the detection of SARS-CoV-2 (IgM/IgG) antibodies by immunochromatographic assay. Data were analyzed using STATA version 15. <br/><br/>Results: The mean age of the enrolled participants was 46.4 ± 11.1 years. The overall seropositivity (IgG + IgM) of SARS-CoV-2 antibodies was 79/150 (52.7%) [95% CI: 44.4–60.9]. Seropositivity of IgM only was 8/150 (5.3) [95% CI: 1.7–8.8], while that of IgG only was 61/150 (40.6%) [95% CI: 32.7–48.4]. Seropositivity of both IgG and IgM was observed in 10/150 (6.7%) patients. In a multivariate logistic regression analysis, history of sore throat (OR: 6.34, 95% CI: 2.305–18.351, p < 0.001), low CD4 count (OR: 0.99, 95% CI: 0.995–0.999, p = 0.004), and use of pit latrines (OR: 2.30, 95% CI: 1.122–4.738, p = 0.023) were independently associated with SARS-CoV-2 seropositivity. <br/><br/>Conclusion: HIV-infected individuals with history of sore throat, low CD4 count, and use of pit latrines were more likely to be SARS-CoV-2 IgG seropositive. There is a need to routinely screen for SARS-CoV-2 infection among HIV-infected individuals to obtain comprehensive data regarding the interactions of the pathogens. |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | HIV |
| General subdivision | SARS-CoV-2 |
| General subdivision | Mwanza |
| General subdivision | Tanzania |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Fuller form of name | Mariam M. Mirambo |
| Fuller form of name | Fabian Chacha |
| Fuller form of name | Nyambura Moremi |
| Fuller form of name | Mohamed Mohamed |
| Fuller form of name | Phares C. Lutema |
| Fuller form of name | Betrand Msemwa |
| Fuller form of name | James Samwel Mundamshimu |
| Fuller form of name | Bartholomeo Nicholaus |
| Fuller form of name | Stephen E. Mshana |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.3390/covid3040031">https://doi.org/10.3390/covid3040031</a> |
| Link text | https://doi.org/10.3390/covid3040031 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | RESEARCH ARTICLES |
| Suppress in OPAC | |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 06/07/2024 | 20240607202457.0 | 06/07/2024 | 06/07/2024 | RESEARCH ARTICLES |