Aetiology of ear infection and antimicrobial susceptibility pattern among patients attending otorhinolaryngology clinic at a tertiary hospital in Dar es Salaam, Tanzania (Record no. 27987)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 03278nam a22003737a 4500 |
| 001 - CONTROL NUMBER | |
| control field | 20240607185814.0 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | 20240607185814.0 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240607191622.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240607b |||||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | Online ISSN: 2044-6055 |
| International Standard Serial Number | Print ISSN: 2044-6055 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | ddc |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Fuller form of name | Aminiel Shangali |
| 245 ## - TITLE STATEMENT | |
| Title | Aetiology of ear infection and antimicrobial susceptibility pattern among patients attending otorhinolaryngology clinic at a tertiary hospital in Dar es Salaam, Tanzania |
| Remainder of title | a hospital-based crosssectional study |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania : |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences [CUHAS-Bugando] : |
| Date of publication, distribution, etc. | 2023 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | Pages 01-08 |
| Extent | Includes References |
| 490 ## - SERIES STATEMENT | |
| Volume/sequential designation | BMJ Open 2023;13:e068359. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract :<br/><br/>Objectives : To determine the aetiological pathogens causing ear infections and their antimicrobial susceptibility patterns among patients with ear complaints at a tertiary hospital in Dar es Salaam.<br/><br/>Design : Hospital-based cross-sectional study.<br/><br/>Settings : Otorhinolaryngology clinic at Muhimbili National Hospital, Dar es Salaam, Tanzania.<br/><br/>Participants : Patients presenting with signs and symptoms of ear infection.<br/><br/>Main outcome measure : Bacteria and fungi isolated from ear swab specimens of patients presenting with signs and symptoms of ear infection; and antimicrobial susceptibility patterns of isolated bacteria.<br/><br/>Results : Two hundred and fifty-five participants were enrolled, with a median age of 31 years and an IQR of 15–49. Otitis externa was the predominant type of ear infection, accounting for 45.1%. We observed positive bacteria culture in 53.3% of study participants, in which 41% of isolates were obtained from patients with chronic suppurative otitis media. Moreover, Staphylococcus aureus (27.3%) and Pseudomonas aeruginosa (24.2%) were the most frequently isolated bacteria, while Candida spp, 12 (63.8%) and Aspergillus spp, 9 (36.2%) were the only isolated fungi. Furthermore, we report that 93% of isolated Enterobacterales were resistant to amoxicillin/clavulanic acid, and 73% were resistant to ceftazidime. In addition, we detected 34.4% extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE) and 44.4% methicillin-resistance S. aureus (MRSA). We also found that 22% of the bacteria isolates were resistant to ciprofloxacin, a primary topical antibiotic used in managing ear infections.<br/><br/>Conclusions : The findings from this study reveal that the leading aetiological agent of ear infection is bacteria. Furthermore, our findings show a significant proportion of ESBL-PE and MRSA-causing ear infections. Hence, detecting multidrug-resistant bacteria is crucial to improving ear infection management. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Fuller form of name | Doreen Kamori |
| Fuller form of name | Willybroad Massawe |
| Fuller form of name | Salim Masoud |
| Fuller form of name | Upendo Kibwana |
| Fuller form of name | Anthony G Mwingwa |
| Fuller form of name | Anselmo Manisha |
| Fuller form of name | Ambele M Mwandigha |
| Fuller form of name | Mariam M Mirambo |
| Fuller form of name | Stephen E Mshana |
| Fuller form of name | Joel Manyahi |
| Fuller form of name | Mtebe Majigo |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1136/bmjopen-2022-068359">https://doi.org/10.1136/bmjopen-2022-068359</a> |
| Link text | https://doi.org/10.1136/bmjopen-2022-068359 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | RESEARCH ARTICLES |
| Suppress in OPAC | |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 06/07/2024 | 20240607185814.0 | 06/07/2024 | 06/07/2024 | RESEARCH ARTICLES |