Influence of Neuro Oncology Capacity Development on Diagnosis of Pediatric Primary CNS Tumors in Northern Tanzania (Record no. 27983)

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000 -LEADER
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001 - CONTROL NUMBER
control field 20240607182256.0
003 - CONTROL NUMBER IDENTIFIER
control field 20240607182256.0
005 - DATE AND TIME OF LATEST TRANSACTION
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008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number Online ISSN 1538-7755
International Standard Serial Number Print ISSN 1055-9965
040 ## - CATALOGING SOURCE
Transcribing agency ddc
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
100 ## - MAIN ENTRY--PERSONAL NAME
Fuller form of name Kristin Schroeder
245 ## - TITLE STATEMENT
Title Influence of Neuro Oncology Capacity Development on Diagnosis of Pediatric Primary CNS Tumors in Northern Tanzania
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania :
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences [CUHAS-Bugando] :
Date of publication, distribution, etc. 2023
300 ## - PHYSICAL DESCRIPTION
Extent Includes References
490 ## - SERIES STATEMENT
Volume/sequential designation Cancer Epidemiol Biomarkers Prev (2023) 32 (6_Supplement): 54.
520 ## - SUMMARY, ETC.
Summary, etc. Abstract :<br/><br/>Purpose: The diagnosis of CNS tumors requires a multidisciplinary team including oncologists, neurosurgeons, radiologists and pathologists. We review the impact of expanding diagnostic capacity on the identification and diagnosis of primary pediatric CNS tumors at Bugando Medical Centre (BMC), the regional cancer referral hospital in the lake zone region of Mwanza Tanzania.<br/><br/>Methods: Patients who presented to BMC from 2016-2022 and received a radiographic or pathologic diagnosis of primary brain or spinal cord tumor were included a CNS tumor registry. Collected data included basic demographics, most specific diagnosis, and diagnostic method. Data was measured and compared before and after initiating key capacity development milestones: 2018 – installation of CT scan, 2020 – arrival of neurosurgical specialist, 2021 – initiation of multidisciplinary tumor board and WhatsApp chat.<br/><br/>Results: A total of 7 spinal and 71 brain tumors were diagnosed among patients aged < 18yo, with (46%) female (n=31) and average age of 7 years. The number of cases per year increased from 3 in 2016, to 17 in 2022. Prior to availability of CT scan (2016-2017), there were an average of 2.5 cases/year, compared to 14.6/year in 2018-2022. With the arrival of the neurosurgeon in 2020, the number of diagnoses/year increased from 11 to 20 from the year prior, but only 50% of patients had a confirmed radiologic or histologic diagnosis. Following initiation of Multidisciplinary Tumor Board Discussion and WhatsApp group, 88% of patients registered in 2022 had a radiographic or histologic diagnosis.<br/><br/>Conclusion: This retrospective study demonstrated the step wise influence of key development milestones on the diagnostic capacity for CNS tumors in a LMIC. While introduction of CNS imaging allowed the identification of more tumors, the multidisciplinary team discussion of the imaging, clinical presentation and pathology results had the greatest overall impact on diagnostic capacity in our setting and should be a key component in future program development.<br/><br/>
700 ## - ADDED ENTRY--PERSONAL NAME
Fuller form of name Taryn Kerley
Fuller form of name James Lubuulwa
Fuller form of name Margreth Magambo
Fuller form of name Jacqueline Kamanga
Fuller form of name Heronima Joas
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1158/1538-7755.ASGCR23-Abstract-54">https://doi.org/10.1158/1538-7755.ASGCR23-Abstract-54</a>
Link text https://doi.org/10.1158/1538-7755.ASGCR23-Abstract-54
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type RESEARCH ARTICLES
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Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Date acquired Total checkouts Barcode Date last seen Price effective from Koha item type
          MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO 06/07/2024   20240607182256.0 06/07/2024 06/07/2024 RESEARCH ARTICLES
Catholic University of  Health and Allied Sciences - CUHAS
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