The efficacy of maternal health education and maternal screening on knowledge and the uptake of infant screening for sickle cell disease in Dar-Es-Salaam, Tanzania (Record no. 27970)

MARC details
000 -LEADER
fixed length control field 03868nam a22004217a 4500
001 - CONTROL NUMBER
control field 20240607151020.0
003 - CONTROL NUMBER IDENTIFIER
control field 20240607151020.0
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240607151814.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1471-2458
040 ## - CATALOGING SOURCE
Transcribing agency ddc
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
100 ## - MAIN ENTRY--PERSONAL NAME
Fuller form of name Hilda J. Tutuba
245 ## - TITLE STATEMENT
Title The efficacy of maternal health education and maternal screening on knowledge and the uptake of infant screening for sickle cell disease in Dar-Es-Salaam, Tanzania
Remainder of title a quasi-experimental study
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania :
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences [CUHAS-Bugando] :
Date of publication, distribution, etc. 2023
300 ## - PHYSICAL DESCRIPTION
Extent Pages 01-12
Extent Includes References
490 ## - SERIES STATEMENT
Volume/sequential designation BMC Public Health volume 23, Article number: 70 (2023)
520 ## - SUMMARY, ETC.
Summary, etc. Abstract :<br/><br/>Background : Globally, Sickle cell disease (SCD) is one of the most common genetic disease with high childhood mortality. Early identification of babies with SCD through newborn screening (NBS) and linking them to care are among the recommended interventions. The purpose of this study was to assess the efficacy of maternal health education and maternal screening for SCD on knowledge and the uptake of infant screening for SCD among mother-infant pairs attending antenatal clinics at Government health facilities in Dar-es-salaam, Tanzania. <br/><br/>Methods : This study was a pre-test post-test, quasi-experimental which involved pregnant women attending antenatal clinics at three hospitals; Mbagala hospital, Sinza hospital and Buguruni health center in Dar Es Salaam. A structured questionnaire was used in data collection. Knowledge on SCD was assessed for all participants before and after two sessions of health education. Participants in Mbagala and Buguruni were also screened for SCD using Sickle SCAN point-of-care test (BioMedomics Inc, USA). The efficacy for health education intervention was computed as the post-intervention minus baseline knowledge score. For proportions, a two-sample z-test was used. Univariate and multivariate logistic regression were used to analyze the efficacy of health education intervention and also predictors of infant diagnosis. <br/><br/>Results : For two sessions of health education intervention, a total of 467 pregnant women completed the sessions. During antenatal visits, a total of 218 were screened for SCD. The proportion of participants with good knowledge of SCD had significantly increased to 85.9% from 12.4% at baseline following the education intervention. In multivariate analysis, sharing the received education on SCD was an independent predictor of the efficacy of health education intervention. Maternal occupation, maternal SCD status as well as sharing the received education on SCD were independent predictors of the uptake of SCD infant diagnosis.<br/><br/>Conclusion : This study has demonstrated that maternal health education and maternal screening for SCD are feasible and efficacious interventions in raising knowledge and improving the uptake of infant diagnosis for SCD. These interventions are strongly recommended to be included in the comprehensive care package for pregnant women attending antenatal clinics, particularly in areas with a high burden of SCD.
600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME
General subdivision Sickle cell disease (SCD)
General subdivision Efficacy
General subdivision Health education
General subdivision Maternal screening for SCD
General subdivision Intervention
General subdivision Knowledge
General subdivision Infant screening
700 ## - ADDED ENTRY--PERSONAL NAME
Fuller form of name Emmanuel Balandya
Fuller form of name Irene K. Minja
Fuller form of name Benson R. Kidenya
Fuller form of name Paschal Ruggajo
Fuller form of name Julie Makani
Fuller form of name Emanuela Marco
Fuller form of name Upendo Masamu
Fuller form of name William Lloyd
Fuller form of name Agnes Jonathan
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1186/s12889-022-14859-2">https://doi.org/10.1186/s12889-022-14859-2</a>
Link text https://doi.org/10.1186/s12889-022-14859-2
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type RESEARCH ARTICLES
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