Prevalence and Associated Factors of Mumps IgG Antibodies among School Aged Children at Mbeya Region in Tanzania (Record no. 22978)

MARC details
000 -LEADER
fixed length control field 03294nam a22003137a 4500
001 - CONTROL NUMBER
control field CUHAS/BM/1001076/T/20
003 - CONTROL NUMBER IDENTIFIER
control field CUHAS/BM/1001076/T/20
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240305194008.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 231101b |||||||| |||| 00| 0 eng d
028 ## - PUBLISHER OR DISTRIBUTOR NUMBER
Source Phone: +255 28 298 3384
Source Fax: +255 28 298 3386
Source Email: vc@bugando.ac.tz
Source Website: www.bugando.ac.tz
035 ## - SYSTEM CONTROL NUMBER
System control number CUHAS/BM/1001076/T/20
040 ## - CATALOGING SOURCE
Language of cataloging English
Transcribing agency DDC
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
Language code of text/sound track or separate title Kiswahili
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Frank Mbugano
Dates associated with a name CUHAS/BM/1001076/T/20
245 ## - TITLE STATEMENT
Title Prevalence and Associated Factors of Mumps IgG Antibodies among School Aged Children at Mbeya Region in Tanzania
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences [CUHAS – Bugando] :
Date of publication, distribution, etc. ©2023
300 ## - PHYSICAL DESCRIPTION
Extent 50 Pages
Extent Includes References and Appendicies
520 ## - SUMMARY, ETC.
Summary, etc. Abstract:<br/><br/>Introduction: Mumps is an acute contagious disease caused by paramyxovirus that affects human mostly characterized by complication such as orchitis, oophoritis, aseptic meningitis, mastitis, encephalopathy, deafness, and spontaneous abortion, although it can be prevented by vaccine. Despite its complications, there is limited information available on the prevalence of the mumps in Tanzania which hinders its control efforts. Only three studies from Tanzania documented on mumps seropositivity of 16.7%, 21.4% and 77% among children. This study aimed at determining the prevalence and associated factors of mumps IgG antibodies among school aged children in Mbeya, Tanzania.<br/><br/>Methodology: A cross sectional study was conducted from May to July 2023, involved 196 school children aged 5-13 years from Ubaruku primary school, Utyego primary school, Mbarali primary school and Mkobwe primary school in rural areas of Mbeya region. Structured questionnaire was b used to collect participant’s social-demographic information and other relevant information. Blood sample was collected, sera was extracted and used for detection of mumps immunoglobulin G antibodies by using indirect Enzyme-Linked Immunosorbent Assay (ELISA) (Vircell, S.L. Parque Technologico de la Salud, Avicena 8, Spain). Data was analyzed by using a STATA version 15.<br/><br/>Results; The median age of enrolled children was 13 (IQR: 8-13) years. Majority of them were female 124 (63.3%). The seropositivity of Mumps IgG antibodies was found to be 174(88.8%, 95% CI: 83.5-92.5). By multivariable logistic regression analysis, history of fever (OR: 5.36 95% CI:1.02-28.22 P=0.047) and sharing utensils (OR: 8.05 95% CI:1.99-32.65 P=0.003) independently predicted Mumps IgG seropositivity.<br/><br/>Conclusion: Mumps IgG seropositivity is extremely high in Mbeya region which suggests that mumps virus is widespread and associated with adverse effects. Increased tendency to share utensils increases the likelihood of exposure. In order to establish an evidence-based control intervention that will help introduce mumps vaccination in Tanzania, further research on magnitude and epidemiology of mumps infection across the nation is required.<br/>
600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME
General subdivision Microbiology & Immunology
General subdivision Medical Laboratory Sciences
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type UNDERGRADUATE DISSERTATIONS
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Date acquired Total checkouts Barcode Date last seen Price effective from Koha item type
            MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO 11/01/2023   CUHAS/BM/1001076/T/2 11/01/2023 11/01/2023 UNDERGRADUATE DISSERTATIONS
Catholic University of  Health and Allied Sciences - CUHAS
Directorate of ICT @ 2024