One year surveillance of cancer of carbapenem resistance gram negative rods and vancomycin resistance gram positive bacteria at at Bugando Medical Centre, Mwanza Tanzania (Record no. 22697)

MARC details
000 -LEADER
fixed length control field 03480nam a22003017a 4500
001 - CONTROL NUMBER
control field CUHAS/BM/1000845/T/19
003 - CONTROL NUMBER IDENTIFIER
control field CUHAS/BM/1000845/T/19
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240305193958.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 221213b |||||||| |||| 00| 0 eng d
028 ## - PUBLISHER OR DISTRIBUTOR NUMBER
Source Phone: +255 28 298 3384
Source Fax: +255 28 298 3386
Source Email: vc@bugando.ac.tz
Source Website: www.bugando.ac.tz
035 ## - SYSTEM CONTROL NUMBER
System control number CUHAS/BM/1000845/T/19
040 ## - CATALOGING SOURCE
Language of cataloging English
Transcribing agency DDC
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
Language code of text/sound track or separate title Kiswahili
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Erick Timas Meremo
Dates associated with a name CUHAS/BM/1000845/T/19
9 (RLIN) 47330
245 ## - TITLE STATEMENT
Title One year surveillance of cancer of carbapenem resistance gram negative rods and vancomycin resistance gram positive bacteria at at Bugando Medical Centre, Mwanza Tanzania
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences [CUHAS – Bugando] :
Date of publication, distribution, etc. ©18.05.2022
300 ## - PHYSICAL DESCRIPTION
Extent 42 Pages
Extent Includes References and Appendices
520 ## - SUMMARY, ETC.
Summary, etc. Abstract:<br/> <br/>Background: The burden of antimicrobial resistance is rapidly growing across antibiotic classes, with increased detection of isolate resistant to carbapenems and vancomycin. The emergency of resistant to carbapenems in GNB, including enterobactericeae, Pseudomonas aeuroginosa and Acinetobacter species, over the last decade has become a major public health crisis worldwide, because of their rapid spread and lack of development of new antimicrobial drugs. The emergency of vancomycin enterococci during the last decade has made difficult to treat nosocomial infections. <br/><br/>This study aimed to determine the surveillance of carbapenem resistance gram negative rods and vancomycin resistance gram positive bacteria at Bugando Medical Center.<br/><br/>Methodology: This was an analytical cross sectional-based study, involving 350 isolates from different samples collected between October 2020 to October 2021 at Bugando Medical Center.Using simple random sampling method, the isolates were selected and proportion of carbapenem resistance and vancomycin resistance were established. Thegram-negativerodsisolates were grown in Muller Hinton Agar [MHA] and examined for the pattern of carbapenamaseresistance using Modified Hodge Test technique.Data were analyzed by STATA version 13.<br/><br/>Results: The mean age of enrolled participants was 31[SD ±26] years. Majority were female 50.5%(960/1902). The overall prevalence of Carbapenem resistance gram negative rods and vancomycin resistance gram positive rods are 12.6%(174/1385)[95% CI: 0.108-0.143] and 32.5%(168/517)[95% CI:0.285-0.367] respectively. Being in-patient (OR: 1.09, 95% CI: 0.73-1.65, P=0.046) and (OR: 2.51, 95%CI: 1.76-3.60, P=0.000) was significantly associated with vancomycin resistance gram positive bacteria and carbapenem resistance gram negative rods respectively.Being male (OR:1.93, 95%CI: 1.37-2.71, P=0.000), also showed association with carbapenem resistance gram negative rods.<br/><br/>Conclusion:This study observed an increase in prevalence of carbapenem-resistance gram negative rods and vancomycin-resistance gram positive bacteria in Mwanza, Tanzania.We recommend routine testing for carbapenem resistance among the MDRGNB and vancomycin resistance(VRSA/VRE) in our hospital and other health facilities in developing countries where there is high prevalent CREs and VREs.<br/>
600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME
General subdivision Microbiology & Immunology
9 (RLIN) 27748
General subdivision Medical Laboratory Sciences
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 26655
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type UNDERGRADUATE DISSERTATIONS
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Barcode Date last seen Copy number Price effective from Koha item type
            MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO   12/13/2022   CRECU/2323 12/13/2022 CRECU/2323 12/13/2022 UNDERGRADUATE DISSERTATIONS
Catholic University of  Health and Allied Sciences - CUHAS
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