Prevalence of virological failure and associated factors among patients on first line antiretroviral therapy at Bugando Medical Centre, Mwanza Tanzania (Record no. 22386)

MARC details
000 -LEADER
fixed length control field 02779nam a22002897a 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240305193936.0
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fixed length control field 220203b |||||||| |||| 00| 0 eng d
028 ## - PUBLISHER OR DISTRIBUTOR NUMBER
Source Phone: +255 28 298 3384
Source Fax: +255 28 298 3386
Source Email: vc@bugando.ac.tz
Source Website: www.bugando.ac.tz
040 ## - CATALOGING SOURCE
Transcribing agency Data centre
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
Language code of text/sound track or separate title Kiswahili
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Sumaiya Suleiman Mohamed
Dates associated with a name CUHAS/MD/4002094/T/17
9 (RLIN) 30453
245 ## - TITLE STATEMENT
Title Prevalence of virological failure and associated factors among patients on first line antiretroviral therapy at Bugando Medical Centre, Mwanza Tanzania
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences [CUHAS – Bugando]
Date of publication, distribution, etc. ©06.08.2021
300 ## - PHYSICAL DESCRIPTION
Extent ix; 38 Pages
Extent Includes References and Appendices
520 ## - SUMMARY, ETC.
Summary, etc. Abstract:<br/><br/>Introduction; Viral suppression among people living with HIV is the main goal of antiretroviral therapy (ART). Despite the treatment, more than four million people patients globally had virological failure in 2017(1). The aim of this study is to assess the prevalence of virological failure and associated factors among patient on first line antiretroviral therapy at Bugando Medical Center.<br/><br/>Background; Despite effective therapies, virological failure (VF) is inevitable in some HIVinfected patients on treatment. In SSA, rates of ART failure vary between 11.1% and 24% in the first 12 months after ART initiation and ∼71%–90% of patients with ART failure have evidence of resistance(2). Common causes of treatment failure in these settings include poor adherence to medication, drug toxicities and use of antiretroviral with lower genetic barriers.<br/><br/>Methodology; A cross sectional study will be conducted at Bugando Medical Center among patients on first line antiretroviral therapy who are 18 years and above. Non-probability sampling will be used to select participants. Data will be collected using semi-structured questionnaires and will be analyzed using SPSS software version 20.<br/><br/>Results; Reduced prevalence of virological failure of new regimens of first line ART. A single important and independent factor which is poor adherence shown to result in virological failure of ART.<br/><br/>Conclusion; This study provided baseline information on prevalence of virological failure among HIV patients on first-line ART and their socio-demographic and clinical characteristics hence, the evidence to show the effectiveness of new ART regimen on viral load suppression, which will help for further researches on this field.<br/>
600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME
General subdivision Internal Medicine
9 (RLIN) 15587
General subdivision Biochemistry
9 (RLIN) 15676
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 22760
9 (RLIN) 26662
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type UNDERGRADUATE DISSERTATIONS
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            MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO   02/03/2022   UD2606 02/03/2022 02/03/2022 UNDERGRADUATE DISSERTATIONS
Catholic University of  Health and Allied Sciences - CUHAS
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