Quality Attributes of Furosemide Syrup Compounded at Bugando Medical Centre Compounding Unit in Mwanza, Tanzania (Record no. 22178)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02419nam a22001697a 4500 |
| 001 - CONTROL NUMBER | |
| control field | CUHAS/BP/3000444/T/17 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 211210b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Elisha F Msigwa |
| Dates associated with a name | CUHAS/BP/3000444/T/17 |
| 9 (RLIN) | 26668 |
| Relator term | Undergraduate Ethical Clearance Certificate Certificate No. 1830/2021 |
| 245 ## - TITLE STATEMENT | |
| Title | Quality Attributes of Furosemide Syrup Compounded at Bugando Medical Centre Compounding Unit in Mwanza, Tanzania |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania: |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences [CUHAS - Bugando] : |
| -- | Phone: +255 28 298 3384 : |
| -- | Fax: +255 28 298 3386 |
| -- | Email: vc@bugando.ac.tz |
| -- | Website: www.bugando.ac.tz : |
| Date of publication, distribution, etc. | ©09 September 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | xi; 25 Pages |
| Extent | Includes References and Appendices |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract:<br/><br/>Background: Furosemide is a potent loop diuretic used in the treatment of oedematous states associated with cardiac, renal and hepatitis failure, and for the treatment of hypertension. In Tanzania Furosemide is a diuretic indicated for the treatment of hypertension. The use of Furosemide at high doses greater than 80mg per day leads high risk of hypokalemia, mild decrease in total thyroid hormone, dehydration, reduced blood volume, electrolyte imbalance. <br/><br/>Methodology: Microbial load determination test and assay test were the laboratory procedures conducted to the triplicate samples to assess the quality of Furosemide syrup for day 1, day 7 and day 14 at Tanzania Medical Devices and Drug Authority laboratories in Mwanza, Tanzania. <br/><br/>Results and Discussion: For the assay test the concentration of compounded furosemide syrup within its shelf life for all the days including day 1, day 7 and 14 were with slight variations but within the required range for its activity. For the microbial load determination test the compounded Furosemide syrup sample for day 1 and day 7 were all negative for both E. coli and P. aeruginosa but for day 14 compounded Furosemide syrup sample tested positive for P. aeruginosa. <br/><br/>Conclusion: The results that compounded Furosemide syrup passed assay test for all the days, day 1, day 7 and 14 but for the microbial load determination test compounded Furosemide syrup passed on day 1 and day 7 but failed the test on day 14 due to P. aeruginosa contamination hence making it not safe for use on day 14. <br/> |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Pharmacy |
| 9 (RLIN) | 26693 |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 26669 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | UNDERGRADUATE DISSERTATIONS |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 12/10/2021 | UD2440 | 12/10/2021 | 12/10/2021 | UNDERGRADUATE DISSERTATIONS |