Antimicrobial Consumption and Resistance Profile of E.Coli Isolates Evaluation among Hospitalized Patients in Magu, Mwanza-Tanzania. (Record no. 21156)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03115nam a22002177a 4500 |
| 001 - CONTROL NUMBER | |
| control field | CUHAS/MD/4001517/T/15 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210810b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mohammed, Hussein. Salila |
| 9 (RLIN) | 21214 |
| Dates associated with a name | CUHAS/MD/4001517/T/15 |
| Relator term | Undergraduate Ethical Clearance Certificate No. 1228/2019 |
| 245 ## - TITLE STATEMENT | |
| Title | Antimicrobial Consumption and Resistance Profile of E.Coli Isolates Evaluation among Hospitalized Patients in Magu, Mwanza-Tanzania. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania: |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences [CUHAS - Bugando] : |
| -- | Phone: +255 28 298 3384 : |
| -- | Fax: +255 28 298 3386 : |
| -- | Email: vc@bugando.ac.tz : |
| -- | Website: www.bugando.ac.tz : |
| Date of publication, distribution, etc. | ©18.09.2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | ix; 35 Pages |
| Extent | Includes References and Appendices |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract: <br/><br/>Background: Antimicrobial is a general term refers to a group of drugs that includes antibiotics, antifungals, antiprotozoal, and antivirals. Antimicrobial resistance develops when microbes, including bacteria, fungi, parasites, and viruses, no longer respond to a drug that previously treated them effectively. Antibiotics are often used for therapy of infected humans and animals. Tanzania is one of the sub-Saharan African countries facing increasing numbers of health care associated infections due to multi-drug resistant Gram-negative bacteria. Data regarding ESBL isolates in Tanzania are limited to tertiary hospital based studies only. <br/><br/>Methodology: It was a point prevalence study that was performed and 59 rectal swab/stool specimens were taken from inpatients who presented at 8 a.m. 8th May 2019 at Magu hospital. Data collection was to be done through filling of questionnaires for the participants of antibiotic consumption. The rectal swabs/stool were cultured on MacConkey agar plate which also contained cefotaxime (2 mcg/ml). Subsequently biochemical tests like Triple sugar iron agar, Sulphide indole mortality medium, citrate test and urease were performed for bacterial identification. Sensitivity test was conducted by disc diffusion on Muller—Hinton agar, for ESBL E. coli Double disc synergy test was done. DDD was found by interview and from medical record then dividing total DDD with total number of participant’s time 100. <br/><br/>Results: 43.8% (21/48) were on antibiotic; most prescribed antibiotic was amoxicillin 61.8% (13/21). A total DDD was 14.741 which is equivalent to 30.71 DDD/100 bed days. 42.4% (25/59) showed positive growth of bacteria 40% (10/25) were K.pnemoniae followed by E. coli 36% (9/25). E. coli was completely resistance to amoxicillin and ceftriaxone.<br/><br/>Conclusion: Isolates E. coli were resistant to commonly used antibiotics such as amoxicillin and ceftriaxone. Hence, immediate action is needed to control antibiotic consumption and prevent resistant bacteria spreading in the community and healthcare facilities. <br/> |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Microbiology and Immunology |
| 9 (RLIN) | 48529 |
| General subdivision | Parasitology |
| 9 (RLIN) | 30263 |
| General subdivision | Pharmacy |
| 9 (RLIN) | 26693 |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 19693 |
| 9 (RLIN) | 19633 |
| 9 (RLIN) | 26705 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | UNDERGRADUATE DISSERTATIONS |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 08/10/2021 | UD1113 | 08/10/2021 | 08/10/2021 | UNDERGRADUATE DISSERTATIONS |