Extent and Management of Chemotherapy Induced Haematological Complications Among Breast Cancer Patients Attending at Bugando Medical Centre Oncology Departmet. (Record no. 20962)

MARC details
000 -LEADER
fixed length control field 03352nam a22003137a 4500
001 - CONTROL NUMBER
control field CUHAS/BP/3000283/T/15
003 - CONTROL NUMBER IDENTIFIER
control field CUHAS/BP/3000283/T/15
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240305193844.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210809b |||||||| |||| 00| 0 eng d
028 ## - PUBLISHER OR DISTRIBUTOR NUMBER
Source Wurzburg Road 35, BMC Premises, Post Code: 33102:
Source P. O. Box 1464, Mwanza – Tanzania:
Source Phone: +255 28 298 3384:
Source Fax: +255 28 298 3386:
Source Email: vc@bugando.ac.tz :
Source www.bugando.ac.tz
035 ## - SYSTEM CONTROL NUMBER
System control number CUHAS/BP/3000283/T/15
040 ## - CATALOGING SOURCE
Language of cataloging English
Transcribing agency DDC
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
Language code of text/sound track or separate title Kiswahili
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Songati, Gendero. Aurelia
Dates associated with a name CUHAS/BP/3000283/T/15
9 (RLIN) 20972
245 ## - TITLE STATEMENT
Title Extent and Management of Chemotherapy Induced Haematological Complications Among Breast Cancer Patients Attending at Bugando Medical Centre Oncology Departmet.
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences [CUHAS – Bugando] :
Date of publication, distribution, etc. ©2019
300 ## - PHYSICAL DESCRIPTION
Extent xi; 27 Pages
Extent Includes References
520 ## - SUMMARY, ETC.
Summary, etc. Abstract: <br/><br/>Background: Breast cancer is one the commonest malignancy in the world and second leading cause of incidence and mortality in women in Tanzania. Together with other management approaches like radiation and surgery (mastectomy), chemotherapy is widely used and it is associated with haemotological complications (anaemia, Neutropenia and thrombocytopenia) due to its mylelosuppressive and cytotoxic effects. <br/><br/>Methods: A retrospective cross sectional hospital study was done in oncology department, Bugando medical centre Mwanza, Tanzania from January 2013 to December 2018. The study included 130 patients’ files which were selected using consecutive sampling. The data collected was recorded in the study tool then filled and analysed by SPSS version 20.<br/><br/>Results and discussion: Mean age of participants was 50.59 years with standard deviation of 12.291. Most of patients were females 94% (n=122). Most of patients 51.5% (n=67) did not develop anaemia during their chemotherapy treatment, 26.9% (n=35) patients had mild anemia, 19.2% (n=25) patients had moderate anemia and 2.4% (n=3, severe anemia was managed by using iron supplements like Fefo and delay of chemotherapy treatment. 35.3% (n=44) patients did not develop neutropenia, 26.2% (n=34), 36 (27.7%), and 10.8% (n=14) patients had mild, moderate and severe neutropenia. Neutropenia was managed by filgrastrim, dose delay and the use of antibiotics like amoxclav as prophylaxis for infections. 80.8% (n=105) did not develop thrombocytopenia 7.7% (n=10), 5.4% (n=7), 3.8% (n=5) and 2.3% (n=3) patients developed grade one, grade two, grade three and grade four thrombocytopenia respectively. Grades three and four thrombocytopenia was managed. <br/><br/>Conclusion: According to this study most of breast cancer patients develop haemotological complications. Therefore Bugando medical centre oncology department should consider the use of filgrastrim and iron supplements as prophylaxis for neutropenia and anaemia. With severe anaemia they should consider blood transfusion so as chemotherapy is not delayed. Also, platelet transfusion and the use of thrombopoietin agents should be conducted in thrombocytopenia. <br/>
600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME
General subdivision Pharmacy
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 19789
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type UNDERGRADUATE DISSERTATIONS
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Barcode Date last seen Price effective from Koha item type
            MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO   08/09/2021   UD0918 08/09/2021 08/09/2021 UNDERGRADUATE DISSERTATIONS
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