Quantification of Brucella SPP Antibodies Titers Among Adult Febrile Patients Sera From Mwanza Tanzania. (Record no. 20859)

MARC details
000 -LEADER
fixed length control field 02964nam a22001937a 4500
001 - CONTROL NUMBER
control field CUHAS/BM/1000260/T/16
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210806b |||||||| |||| 00| 0 eng d
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Emay, Israel. Y
Dates associated with a name CUHAS/BM/1000260/T/16
9 (RLIN) 20819
245 ## - TITLE STATEMENT
Title Quantification of Brucella SPP Antibodies Titers Among Adult Febrile Patients Sera From Mwanza Tanzania.
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences [CUHAS - Bugando]
-- Phone: +255 28 298 3384
-- Fax: +255 28 298 3386
-- Email: vc@bugando.ac.tz
-- Website: www.bugando.ac.tz
Date of publication, distribution, etc. ©18.08.2019
300 ## - PHYSICAL DESCRIPTION
Extent vii; 29 Pages
Extent Includes References and Appendices
520 ## - SUMMARY, ETC.
Summary, etc. Abstract: <br/><br/>Background: Brucellosis is a bacterial zoonotic disease of public health importance especially in agro-pastoralists communities and animal product consumers. It is endemic in many resource limited countries. Most of clinical presentations resemble that of other diseases like malaria which are also endemic in these countries. The routine diagnosis had been challenging due to lack of reliable tests making it difficult to diagnoses active infection due to the fact that presence of Brucella antibodies does not necessarily indicate active infection. <br/><br/>Objective: This study aimed at quantifying the Brucella antibodies forms sera of febrile patients who were found to be positive for Brucella spp antibodies.<br/><br/>Methodology: The was cross sectional laboratory-based study involving 260 sera from Brucella spp. seropositive febrile patients conducted from May to June 2019. Archived sera from febrile patients collected in different hospitals and health centers in Mwanza were retrieved and analyzed. Quantification of the Brucella titers was done by slide agglutination test as per manufacturer’s instructions (Euro cell A/M® Euromaidan equip LTD. UK. Data was analyzed by STATA version 13 as per study objectives. <br/><br/>Results: Median age of enrolled adults febrile patients was 31 (IQR 25-44) years and mean temperature was 37.78 ± 023’C. Among 260 adults febrile patients tested for Brucella antibodies 73(28.08% CI: 22-0.33) were found to have high Brucella antibodies titers. Having big number of family members (OR: 0.88, 95% CI: 0.78-1.00, p=0.03) significantly protected individuals from having high Brucella antibody titters. <br/><br/>Conclusion and Recommendations: The prevalence of high Brucella antibody titers among adults febrile patients is high and big number of household members significantly protected individuals from having high Brucella antibody titters. With decrease trend of malaria fever, brucellosis should be considered in routine diagnosis. According to study findings quantification method can be used in routine diagnosis of Brucellosis <br/><br/>
600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME
General subdivision Microbiology and Immunology
9 (RLIN) 48529
General subdivision Medical Laboratory Sciences
9 (RLIN) 48546
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 19715
9 (RLIN) 19716
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type UNDERGRADUATE DISSERTATIONS
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Barcode Date last seen Price effective from Koha item type
            MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO   08/06/2021   UD0815 08/06/2021 08/06/2021 UNDERGRADUATE DISSERTATIONS
Catholic University of  Health and Allied Sciences - CUHAS
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