Escherichia Coli Serotype O157:H7 In Humans, Domestic Animals and in the Environmental Premises in Mwanza and Shinyanga, Tanzania. (Record no. 20830)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04335nam a22003377a 4500 |
| 001 - CONTROL NUMBER | |
| control field | CUHAS/BM/1000252/T/16 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | CUHAS/BM/1000252/T/16 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240305193836.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210806b |||||||| |||| 00| 0 eng d |
| 028 ## - PUBLISHER OR DISTRIBUTOR NUMBER | |
| Source | Wurzburg Road 35, BMC Premises, Post Code: 33102: |
| Source | P. O. Box 1464, Mwanza – Tanzania: |
| Source | Phone: +255 28 298 3384: |
| Source | Fax: +255 28 298 3386: |
| Source | Email: vc@bugando.ac.tz : |
| Source | www.bugando.ac.tz |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | CUHAS/BM/1000252/T/16 |
| 040 ## - CATALOGING SOURCE | |
| Language of cataloging | English |
| Transcribing agency | DDC |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| Language code of text/sound track or separate title | Kiswahili |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Nyanda, Boaz. M |
| Dates associated with a name | CUHAS/BM/1000252/T/16 |
| 9 (RLIN) | 20767 |
| 245 ## - TITLE STATEMENT | |
| Title | Escherichia Coli Serotype O157:H7 In Humans, Domestic Animals and in the Environmental Premises in Mwanza and Shinyanga, Tanzania. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania: |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences [CUHAS – Bugando] : |
| Date of publication, distribution, etc. | ©2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | vii; 43 Pages |
| Extent | Includes References |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract:<br/><br/>Background: Diarrhea due to Escherichia coli serotype O157:H7 is one of the leading causes of morbidity and mortality globally among enteropathogens. Previous study conducted in Mwanza Tanzania on diarrhea among under five children was based on detection of Shiga Toxin Producing Escherichia coli (STEC). This study aim to add more information (in addition of under five children with diarrhea) by including domestic and their surrounding environmental premises to determine the prevalence and drug susceptibility pattern of STEC serotype O157:H7 and STEC non O157:H7 isolates in Mwanza and Shinyanga, Tanzania. <br/><br/>Methods: A cross sectional study was conducted involving under five children with diarrhea, domestic animals and environmental specimens between May to July 2018 and 2019 in Mwanza and Shinyanga, Tanzania. Stool samples from children with diarrhea, recto-fecal samples from domestic animals and selected environmental samples (such as juices, salad, and water) were collected and cultured on MacConkey agar and CHROMO agar to identify Escherichia coli and STEC, respectively. Then, all STEC isolates were cultured in Sorbitol MacConkey agar to identify STEC serotype O157:H7. Demographic and clinical information were collected using a standard tool and STATA software version 13.0 used for data analysis. <br/><br/><br/>Results: Out of 355 stool samples of under five children, 290 (86.7%) had positive culture results, where by 220 (62%) samples were positive for E. coli. Out of 220 E. coli, 45 (20.5%) were STEC positive and out 45 positive STEC, 5 (11.1%) were O157H7. Out of 285 animal specimens, 217 (76.1%) had positive culture results, where by 204 (71.6%) were positive for E. coli. Out of 204 E. coli, 52 (25.5%) were STEC positive and out of 52 STEC positive, 7 (13.5%) were O157H7. Out of 142 environmental specimens collected, 56 (39.4%) had positive culture results, where by 15 (10.6%) were positive for E. coli. Out of 15 E. coli, 5 (33.3%) were STEC positive and out of 5 STEC strains, 3 (60%) were O157H7. Children under five years of age residing in urban areas had higher STEC (28.4%) than those residing in the rural areas (17.0%), although the association was not statistically significant (p-value=0.058). STEC was significantly associated with domestic animals residing in Sengerema (20.5%) and Shinyanga (34.6%) compared to Mwanza (7.0%), P-value <0.001. STEC was also associated with chicken (22.0%) and pigs (33.3%) compared to other domestic animals (p-value=0.013)<br/><br/>Conclusions: The proportions of STEC among E. coli strains in three interfaces is high but the proportions of E. coli O157:H7 is low. Of note, STEC strains were more associated children in urban areas, and also in chicken and pigs. <br/><br/>Significance: This study added more information on the STEC and STEC O157:H7 as potential causes of diarrhea among children under five years of ages, and also evaluated the potential source of these pathogens among domestic animals and environmental premises. These is turn will help in the institution of specific preventive measures using One Health Approach. <br/> |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Medical Laboratory Sciences |
| General subdivision | Microbiology & Immunology |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 19713 |
| 9 (RLIN) | 20768 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | UNDERGRADUATE DISSERTATIONS |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 08/06/2021 | UD0787 | 08/06/2021 | 08/06/2021 | UNDERGRADUATE DISSERTATIONS |