Evaluation of Bacteriacidal Effect of Medium Chain Fatty Acids Found in Cocos nucifera L. Fixed Oils on Lipid Coated Bacteria Causing Neonatal Sepsis. (Record no. 20476)

MARC details
000 -LEADER
fixed length control field 02849nam a22003377a 4500
001 - CONTROL NUMBER
control field CUHAS/BP/3000099/T/13
003 - CONTROL NUMBER IDENTIFIER
control field CUHAS/BP/3000099/T/13
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240305193820.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210802b |||||||| |||| 00| 0 eng d
028 ## - PUBLISHER OR DISTRIBUTOR NUMBER
Source Wurzburg Road 35, BMC Premises, Post Code: 33102:
Source P. O. Box 1464, Mwanza – Tanzania:
Source Phone: +255 28 298 3384:
Source Fax: +255 28 298 3386:
Source Email: vc@bugando.ac.tz
Source www.bugando.ac.tz
035 ## - SYSTEM CONTROL NUMBER
System control number CUHAS/BP/3000099/T/13
040 ## - CATALOGING SOURCE
Language of cataloging English
Transcribing agency DDC
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
Language code of text/sound track or separate title Kiswahili
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Bureta, Jackline. N
Dates associated with a name CUHAS/BP/3000099/T/13
9 (RLIN) 20321
245 ## - TITLE STATEMENT
Title Evaluation of Bacteriacidal Effect of Medium Chain Fatty Acids Found in Cocos nucifera L. Fixed Oils on Lipid Coated Bacteria Causing Neonatal Sepsis.
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences [CUHAS – Bugando] :
Date of publication, distribution, etc. ©2017
300 ## - PHYSICAL DESCRIPTION
Extent vii; 18 Pages
Extent Includes References
520 ## - SUMMARY, ETC.
Summary, etc. Abstract: <br/><br/>Background: Coco nucifera L. is a common tree known as coconut tree, it contains triglycerides such as caproic, lauric, oleic, capric myristic and palmitic acids which are said to have antimicrobial activity. Neonatal sepsis is a common problem in our setting with common causative agents being gram negative bacteria of Klebsiella pneumoniae and Escherichia coli and gram positive being Staphlococus aureus with an arising in resistance to drugs there is a need for more effective and safer drugs to tackle this problem there for this study was designed to test the antimicrobial activity of the coconut oil on Klebsiella pneumoniae a common causative agent of neonatal sepsis in or setting. <br/><br/>Methodology: Laboratory investigation conducted at CUHAS multipurpose laboratory using a coconut oil extract and archived ESBL producing Klebsilla pneumoniae obtained from infected neonates blood. After a sub culture a disc diffusion test was done using Muller Hinton agar with the sterile virgin coconut oil. A sensitivity comparison disc diffusion test was done with Meropenem and Gentamycin. <br/><br/>Results and Discussion: of 20 bacterial isolates used showed an activity to coconut oil extract with a median of 9mm and an interquartile range of 8-9mm in diameter, 8(40%) had the zone of inhibition of 9mm in diameter and majority 4(20%) isolates had zone diameter of 10mm. all the isolates were sensitive to gentamycin and 55% sensitive to meropenem. <br/><br/>Conclusion and Recommendation: Coconut oil had activity on ESBL producing Klebsiella pneumoniae but less effective compared to gentamycin and meropenem. <br/>
600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME
General subdivision Pharmacy
General subdivision Microbiology & Immunology
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 19704
9 (RLIN) 19711
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type UNDERGRADUATE DISSERTATIONS
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Barcode Date last seen Price effective from Koha item type
            MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO   08/02/2021   UD0433 08/02/2021 08/02/2021 UNDERGRADUATE DISSERTATIONS
Catholic University of  Health and Allied Sciences - CUHAS
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