Assessment of Physicochemical Quality of Commercially Available Albendazole Brands in Mwanza City. (Record no. 20296)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02652nam a22001937a 4500 |
| 001 - CONTROL NUMBER | |
| control field | CUHAS/BP/3000114/T/13 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210730b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mahuma, Sami. B |
| Dates associated with a name | CUHAS/BP/3000114/T/13 |
| 9 (RLIN) | 20095 |
| Relator term | Undergraduate Ethical Clearance Certificate No. 289/2017 |
| 245 ## - TITLE STATEMENT | |
| Title | Assessment of Physicochemical Quality of Commercially Available Albendazole Brands in Mwanza City. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania: |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences [CUHAS - Bugando] : |
| -- | Phone: +255 28 298 3384 : |
| -- | Fax: +255 28 298 3386 : |
| -- | Email: vc@bugando.ac.tz : |
| -- | Website: www.bugando.ac.tz : |
| Date of publication, distribution, etc. | ©10.08.2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | ix; 25 Pages |
| Extent | Includes References and Appendices |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract: <br/><br/>Introduction: The assessment of physical and chemical quality parameters of a pharmaceutical product using internationally recognized pharmacopoeia is crucial in assuring that only products of acceptable quality circulate in the market. The use of substandard and counterfeit medicinal products has been associated with treatment failure, development of disease causative agent resistance against the drug, adverse drug reactions and sometimes death. Therefore this study aimed to assess physical and chemical parameters of four Albendazole tablets brands as per United States Pharmacopeia (USP 38 NF 33) monographs. The investigated parameters include hardness, mass uniformity for physical and amount of active pharmaceutical ingredient (API), dissolution for chemical parameters. These assessed brands included Alben® (Shelys, Tanzania), Finazol® (Fourrts, India), Zentel® (GSK, South Africa) and Alzental® (Shin Poong, South Korea) which were collected from pharmacies in Mwanza city.<br/><br/>Methods: All samples were prepared according to the standard operating procedures (SOPs) and necessary calculations were made. Then all procedures were done using specified equipment and material, data was then collected and analyzed. <br/><br/>Results: Among the four parameters investigated, only two parameters (mass uniformity and amount of active pharmaceutical ingredient) complied with the USP specifications for all four brands while for the other two (hardness and dissolution) did not comply. Although only one brand. Zentel® complied with the dissolution test.<br/><br/>Conclusion: Therefore the periodic monitoring programs of marketing authorized products are important to ensure the quality of circulating medicine in the market. <br/> |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Pharmacy |
| 9 (RLIN) | 26693 |
| General subdivision | Parasitology |
| 9 (RLIN) | 30263 |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 20068 |
| 9 (RLIN) | 19841 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | UNDERGRADUATE DISSERTATIONS |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 07/30/2021 | UD0253 | 07/30/2021 | 07/30/2021 | UNDERGRADUATE DISSERTATIONS |