Evaluation of Physical Parameters of Selected Brands of Metronidazole Tablets Marketed in Mwanza City. (Record no. 20295)

MARC details
000 -LEADER
fixed length control field 02698nam a22002897a 4500
001 - CONTROL NUMBER
control field CUHAS/BP/3000097/T/13
003 - CONTROL NUMBER IDENTIFIER
control field CUHAS/BP/3000097/T/13
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240305193815.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210730b |||||||| |||| 00| 0 eng d
028 ## - PUBLISHER OR DISTRIBUTOR NUMBER
Source Phone: +255 28 298 3384
Source Fax: +255 28 298 3386
Source Email: vc@bugando.ac.tz
Source Website: www.bugando.ac.tz
040 ## - CATALOGING SOURCE
Transcribing agency DLC
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
Language code of text/sound track or separate title Kiswahili
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Bundala, Victoria. K
Dates associated with a name CUHAS/BP/3000097/T/13
9 (RLIN) 20094
Relator term Undergraduate Ethical Clearance Certificate No. 287/2017
245 ## - TITLE STATEMENT
Title Evaluation of Physical Parameters of Selected Brands of Metronidazole Tablets Marketed in Mwanza City.
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences [CUHAS - Bugando] :
Date of publication, distribution, etc. ©11.08.2017
300 ## - PHYSICAL DESCRIPTION
Extent x; 33 Pages
Extent Includes References and Appendecies
520 ## - SUMMARY, ETC.
Summary, etc. Abstract: <br/><br/>Introduction: Metronidazole is a nitroimidazole drug which is effective in treating anaerobic bacteria, protozoa, trichomonasis, and giardiasis infections. Metronidazole is among essential drugs used in Tanzania and its availability is widely and is sold at cheap price. As there is manufacture’s competition of many brands in Mwanza city. It is estimated that 30-60% of medicines in developing countries are counterfeit which may result in therapeutic failure and thus contributing to drug resistance. <br/><br/>Aim: The aim of this study was to evaluate the quality of different registered unexpired six brands of metronidazole tablets randomly purchased from registered pharmacies of Nyamagana and Ilemela in Mwanza city. <br/><br/>Methodology: The in vitro parameters employed were dissolution test, assay test, hardness test, friability test, and weight variation test carried out at TFDA laboratories headquarters. <br/><br/>Results: The results obtained showed that all brands complied with USP 38 NF 33 specifications except for hardness test which only two brands complied while other four did not comply and for friability test which only one brand did not comply while other five brands complied with the USP 38 NF 33 specifications. <br/><br/>Conclusion: Therefore, it can be concluded that overall quality of brands tested was satisfactory but TFDA should ensure that quality of metronidazole products in the market are regularly monitored and adhere to the requirements of USP 38 NF 33 and Manufacturers all should be advised on making sure that their products are of required quality for all parameters before releasing it to the market. <br/>
600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME
General subdivision Pharmacy
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 19789
9 (RLIN) 19729
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type UNDERGRADUATE DISSERTATIONS
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Barcode Date last seen Price effective from Koha item type
            MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO   07/30/2021   UD0252 07/30/2021 07/30/2021 UNDERGRADUATE DISSERTATIONS
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