In Vitro Evaluation of Nigella Sativa Against Staphylococcus Aureus and Candida Species Isolates in Mwanza, Tanzania (Record no. 20149)

MARC details
000 -LEADER
fixed length control field 02580nam a22001817a 4500
001 - CONTROL NUMBER
control field CUHAS/BP/3000037/T/11
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210728b |||||||| |||| 00| 0 eng d
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Abbas, Shadya
Dates associated with a name CUHAS/BP/3000037/T/11
9 (RLIN) 19810
Relator term Undergraduate Ethcal Clareance Certificate No. 034/2015
245 ## - TITLE STATEMENT
Title In Vitro Evaluation of Nigella Sativa Against Staphylococcus Aureus and Candida Species Isolates in Mwanza, Tanzania
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania :
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences [CUHAS - Bugando] :
-- Phone: +255 28 298 3384 :
-- Fax: +255 28 298 3386 :
-- Email: vc@bugando.ac.tz :
-- Website: www.bugando.ac.tz :
Date of publication, distribution, etc. ©03.08.2015
300 ## - PHYSICAL DESCRIPTION
Extent xi; 22 Pages
Extent Includes References and Appendices
520 ## - SUMMARY, ETC.
Summary, etc. Abstract:<br/><br/>Staphylococcus aureus and Candida species continues to be one of the commonest pathogens encountered in clinical as well as laboratory practice. It is has become a major health problem worldwide. Newer antimicrobial agents of plant source are urgently needed to combat this problem due to their fewer side effects. Nigella sativa oil commonly known as black seed oils was aimed at evaluating if it had any antimicrobial effect to Staphylococcus aureus and Candida species isolates. <br/><br/>Methodology: Antibacterial and antifungal of Nigella sativa oil was studied to 10 isolates of Staphylococcus aureus and 10 isolates of Candida species. Disk agar diffusion technique was used using impregnated filter paper disk on inoculated Mueller Hinton Agar plates and Sabouraud Dextrose Agar plates respectively. Staphylococcus aureus ATCC was used as the standard reference strain. <br/><br/>Results: All bacterial isolates tested (100%) were susceptible to Nigella sativa oil the used standard drugs for Staphylococcus aureus showed highly susceptibility patterns except Cefoxitin (0%) About 40 40%) of candida species isolates were sensitive to Intraconazole, 30% were sensitive to Voriconazole; but all of them (100%) were resistant to Nigella sativa oil. <br/><br/>Conclusion: Nigella sativa oil a promising anti-Staphylococcal plant extract given the high susceptibility pattern shown in Staphylococcus aureus clinical isolates but it lacked antifungal activity to Candida species may be due to crude methods of extraction employed in this study. Further research using extraction methods is recommended so as to reliably ascertain the efficacy of Nigella sativa as reported in other countries. <br/>
600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME
General subdivision Pharmacy
9 (RLIN) 26693
General subdivision Microbiology and Immunology
9 (RLIN) 48529
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 19713
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type UNDERGRADUATE DISSERTATIONS
Holdings
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