In Vitro Antimicrobial Activity of Curcuma Longa Extract Against Pseudomonas Aeruginosa Isolates From Patients with Surgical Site Infections in Mwanza, Tanzania (Record no. 20139)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02504nam a22001817a 4500 |
| 001 - CONTROL NUMBER | |
| control field | CUHAS/BP/3000144/T/14 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210728b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Anyitike, Heberi |
| Dates associated with a name | CUHAS/BP/3000144/T/14 |
| 9 (RLIN) | 19795 |
| Relator term | Undergraduate Ethical Clearance Certificate No. 579/2018 |
| 245 ## - TITLE STATEMENT | |
| Title | In Vitro Antimicrobial Activity of Curcuma Longa Extract Against Pseudomonas Aeruginosa Isolates From Patients with Surgical Site Infections in Mwanza, Tanzania |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania: |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences [CUHAS - Bugando] |
| -- | Phone: +255 28 298 3384 : |
| -- | Fax: +255 28 298 3386 : |
| -- | Email: vc@bugando.ac.tz : |
| -- | Website: www.bugando.ac.tz : |
| Date of publication, distribution, etc. | ©30.08.2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | ix; 20 Pages |
| Extent | Includes References and Appendices |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract:<br/><br/>Background: Pseudomonas aeruginosa is a Gram negative bacteria commonly found in moist environment. It has ability of forming biofilm, making it very resistant to detergents and antimicrobial agents. These properties make it successful is causing nosocomial infections, mostly immunocompromised patients. Curcuma longa has traditionally been used to treat bacteria skin infections, but its antimicrobial therapeutic effects has not been evaluated in Tanzania. <br/><br/>Methodology: Curcuma long methanolic extract was obtained from powder purchased from Tanganyika local market. The extract was used for in-vitro antimicrobial activity testing against P. aeruginosa isolates using disk diffusion method and broth microdilution test. <br/><br/>Results: The MIC of Curcuma long extract against P. aeruginosa clinical isolates from patients with SSI was 0.05g/ml. All 10 P. aeruginosa isolates were sensitive to Curcuma long extract at a concentration of 0.3g/ml, with the overall mean zone of inhibition of 28±2.13 mm. The overall percentage of sensitivities of 10 P. aeruginosa isolates for standard antimicrobial agents tested were: meropenem 100%, gentamicin 90%, ciprofloxacin 100%, ceftazidime 100% and piperacilin-tazobactum 100%. <br/><br/>Conclusions and recommendations: Curcuma long has excellent antimicrobial activity against P. aeruginosa clinical isolates. It is a promising source useful of antimicrobial agent when high technological methods of extracting active ingredients as well as evaluating toxicological profiles are done to ensure patients’ safety. <br/> |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Microbiology and Immunology |
| 9 (RLIN) | 48529 |
| General subdivision | Pharmacy |
| 9 (RLIN) | 26693 |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 19713 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | UNDERGRADUATE DISSERTATIONS |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 07/28/2021 | UD0096 | 07/28/2021 | 07/28/2021 | UNDERGRADUATE DISSERTATIONS |