In Vitro Antifungal Activity of Ocimum Sanctum L. Leaf Extracts on Candida Albicans Clinical Isolates in Mwanza Tanzania (Record no. 20085)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02342nam a22002057a 4500 |
| 001 - CONTROL NUMBER | |
| control field | CUHAS/BP/3000193/T/14 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | Undergraduate Ethical Clearance Certificate No. 543/2018 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210728b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Somaiya, Sejal. P |
| Dates associated with a name | CUHAS/BP/3000193/T/14 |
| 9 (RLIN) | 19702 |
| 245 ## - TITLE STATEMENT | |
| Title | In Vitro Antifungal Activity of Ocimum Sanctum L. Leaf Extracts on Candida Albicans Clinical Isolates in Mwanza Tanzania |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania: |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences [CUHAS - Bugando] : |
| -- | Phone: +255 28 298 3384 : |
| -- | Fax: +255 28 298 3386 : |
| -- | Email: vc@bugando.ac.tz : |
| -- | Website: www.bugando.ac.tz : |
| Date of publication, distribution, etc. | ©30.08.2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | x; 22 Pages |
| Extent | Includes Refferences and Appedices |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract:<br/><br/>Background: Oral candidiasis is amongst the most common opportunistic fungal infections caused mainly by C. albicans. Resistance of C. albicans to the most commonly prescribed antifungal agents such as azoles have been reported even in Tanzania. This imposes the need to explore alternative medicinal products. Plants such as O. sanctum L. are an important source of herbal medicine. <br/><br/>Methodology: Different concentrations of O. sanctum L. leaf extracts; (2.5mg/ml), (5mg/ml), (7.5mg/ml), (10mg/ml), 15mg/ml), (20mg/ml) were made in aqueous solution form and were tested against 20 C. albicans isolates. Agar dilution method using Muller Hinton Agar (MH – Oxoid, UK) supplemented with the different concentrations of the leaf extract was used to test for susceptibility against C. albicans isolates. The minimum concentration that inhibited the growth of C. albicans was considered as Minimum Inhibition concentration (MIC).<br/><br/>Results: A total of 20(100%), 13(65%) and 9(45%) C. albicans isolates were inhibited by O. sanctum L. extract at the concentration of 20mg/ml, 15mg/ml and 10mg/ml, respectively. Our results show the minimum inhibitory concentration of O. sanctum L leaves extract is 20mg/ml. <br/><br/>Conclusion: The study results revealed that the effectiveness of O. sanctum L. leaf extracts on pathogen C. albicans increases with the increased concentrations. <br/> |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Pharmacy |
| 9 (RLIN) | 26693 |
| General subdivision | Microbiology and Immunology |
| 9 (RLIN) | 48529 |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 19703 |
| 9 (RLIN) | 19704 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | UNDERGRADUATE DISSERTATIONS |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 07/28/2021 | UD0042 | 07/28/2021 | 07/28/2021 | UNDERGRADUATE DISSERTATIONS |