Blood pressure, T cells, and mortality in people with HIV in Tanzania during the first 2 years of antiretroviral therapy (Record no. 19944)

MARC details
000 -LEADER
fixed length control field 02603nam a22003377a 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240305193746.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 221206b |||||||| |||| 00| 0 eng d
028 ## - PUBLISHER OR DISTRIBUTOR NUMBER
Source Phone: +255 28 298 3384
Source Fax: +255 28 298 3386
Source Email: vc@bugando.ac.tz
Source Website: www.bugando.ac.tz
040 ## - CATALOGING SOURCE
Language of cataloging English
Transcribing agency DLC
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Karl G Reis
9 (RLIN) 46786
245 ## - TITLE STATEMENT
Title Blood pressure, T cells, and mortality in people with HIV in Tanzania during the first 2 years of antiretroviral therapy
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. The Journal of Clinical Hypertension &
-- Catholic University of Health and Allied Sciences [CUHAS – Bugando]
Date of publication, distribution, etc. 20 August 2020
300 ## - PHYSICAL DESCRIPTION
Extent Pages 1554-1562
490 ## - SERIES STATEMENT
Volume/sequential designation The Journal of Clinical Hypertension Volume 22 Issue 9
520 ## - SUMMARY, ETC.
Summary, etc. <br/>Abstract::<br/><br/>Cardiovascular disease is now a leading cause of mortality in people with HIV (PWH). High blood pressure is the major driver of cardiovascular disease. Despite this, little is known about blood pressure in PWH during the early years of antiretroviral therapy (ART). In this prospective cohort study in Tanzania, the authors conducted unobserved blood pressure measurements at enrollment, 3, 6, 12, 18, and 24 months in 500 PWH initiating ART and 504 HIV-uninfected adults. The authors excluded measurements taken on antihypertensive medications. Although PWH had a significantly lower blood pressure before ART initiation, they had a significantly greater increase in blood pressure during the first 2 years of ART compared to HIV-uninfected controls. Blood pressure correlates in PWH differed from HIV-uninfected controls. In PWH, lower baseline CD4+ T-cell counts were associated with lower blood pressure, and greater increases in CD4+ T-cell counts on ART were associated with greater increases in blood pressure, both on average and within individuals. In addition, PWH with a systolic blood pressure (SBP) <90 mm Hg at the time of ART initiation had ~30% mortality in the following 3 months due to occult infections. These patients require careful investigation for occult infections, and those with tuberculosis may benefit from corticosteroids.<br/>
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 21235
9 (RLIN) 46637
9 (RLIN) 46634
9 (RLIN) 46588
9 (RLIN) 46787
9 (RLIN) 45156
9 (RLIN) 45137
9 (RLIN) 22982
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1111/jch.13975">https://doi.org/10.1111/jch.13975</a>
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type RESEARCH ARTICLES
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Barcode Date last seen Copy number Price effective from Koha item type
            MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO   12/06/2022   RA1152 12/06/2022 RA1152 12/06/2022 RESEARCH ARTICLES
Catholic University of  Health and Allied Sciences - CUHAS
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