Predictors of tuberculosis in first 6 months after initiation of antiretroviral therapy: a case-control study (Record no. 19938)

MARC details
000 -LEADER
fixed length control field 02453nam a22003137a 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240305193746.0
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fixed length control field 221206b |||||||| |||| 00| 0 eng d
028 ## - PUBLISHER OR DISTRIBUTOR NUMBER
Source Phone: +255 28 298 3384
Source Fax: +255 28 298 3386
Source Email: vc@bugando.ac.tz
Source Website: www.bugando.ac.tz
040 ## - CATALOGING SOURCE
Language of cataloging English
Transcribing agency DLC
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Robert N Peck
9 (RLIN) 22982
245 ## - TITLE STATEMENT
Title Predictors of tuberculosis in first 6 months after initiation of antiretroviral therapy: a case-control study
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. International Union Against Tuberculosis and Lung Disease &
-- Catholic University of Health and Allied Sciences [CUHAS – Bugando]
Date of publication, distribution, etc. 2012/8/1
300 ## - PHYSICAL DESCRIPTION
Extent Pages 1047-1051
490 ## - SERIES STATEMENT
Volume/sequential designation The International journal of tuberculosis and lung disease Volume 16 Issue 8
520 ## - SUMMARY, ETC.
Summary, etc. Abstract:<br/><br/>SETTING: In Africa, 10% of human immunodeficiency virus (HIV) infected adults starting antiretroviral therapy (ART) die within the first year, and tuberculosis (TB) is the leading cause of death.<br/><br/>OBJECTIVE: To investigate the predictors of ART-associated TB at an adult HIV clinic in Tanzania.<br/><br/>DESIGN: In this nested case-control study, adults starting ART were screened for TB according to the World Health Organization protocol. Those not diagnosed with TB were observed for 6 months. Patients diagnosed with TB were defined as cases, and controls were selected from among the patients who did not develop TB using incidence density matching.<br/><br/>RESULTS: Among the 2514 HIV-positive adults in our cohort, 72 (3%) were diagnosed with TB during the first 6 months of ART. By multivariate analysis, baseline characteristics predictive of TB were cough, fever and night sweats; 76% (55/72) of the cases had at least one of these symptoms at the time of starting ART.<br/><br/>CONCLUSION: Overall, 75% of the patients who developed TB during the first 6 months of ART had TB symptoms at the time of starting ART. Improved TB diagnostics and/or better strategies for empirical anti-tuberculosis treatment are needed for patients with symptoms of TB at ART initiation.
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 19623
9 (RLIN) 22760
9 (RLIN) 45114
9 (RLIN) 46746
9 (RLIN) 23036
9 (RLIN) 23034
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.5588/ijtld.11.0772">https://doi.org/10.5588/ijtld.11.0772</a>
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type RESEARCH ARTICLES
Holdings
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Catholic University of  Health and Allied Sciences - CUHAS
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