Congenital Zika Virus Infection Paradigm: What is in the Wardrobe? A Narrative Review (Record no. 19607)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03281nam a22002777a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240305193734.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 221122b |||||||| |||| 00| 0 eng d |
| 028 ## - PUBLISHER OR DISTRIBUTOR NUMBER | |
| Source | Phone: +255 28 298 3384 |
| Source | Fax: +255 28 298 3386 |
| Source | Email: vc@bugando.ac.tz |
| Source | Website: www.bugando.ac.tz |
| 040 ## - CATALOGING SOURCE | |
| Language of cataloging | English |
| Transcribing agency | DLC |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mariam M Mirambo |
| 9 (RLIN) | 22927 |
| 245 ## - TITLE STATEMENT | |
| Title | Congenital Zika Virus Infection Paradigm: What is in the Wardrobe? A Narrative Review |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania: |
| Name of publisher, distributor, etc. | East Africa Science & |
| -- | Catholic University of Health and Allied Sciences [CUHAS – Bugando] |
| Date of publication, distribution, etc. | 2019/3/25 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | Pages 49-56 |
| 490 ## - SERIES STATEMENT | |
| Volume/sequential designation | East Africa Science Volume 1 Issue 1 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | ABSTRACT:<br/><br/>Background: Zika virus infection during pregnancy has been recently associated with congenital microcephaly and other<br/>severe neural tube defects. However, the magnitude of confirmed cases and the scope of these anomalies have not been<br/>extensively documented. This review focuses on the magnitude of laboratory-confirmed congenital Zika virus cases among<br/>probable cases and describing the patterns of congenital anomalies allegedly caused by the Zika virus, information which<br/>will inform further research in this area.<br/><br/>Methods: We conducted a literature search for English-language articles about congenital Zika virus infection using online<br/>electronic databases (PubMed/MEDLINE, POPLINE, Embase, Google Scholar, and Web of Knowledge). The search terms<br/>used were, “zika”, “pregnancy”, [year], “microcephaly”, “infants”, “children”, “neonates”, “foetuses”, “neural tube defect”,<br/>and “CNS manifestations” in different combinations. All articles reporting cases or case series between January 2015 and<br/>December 2016 were included. Data were entered into a Microsoft Excel database and analysed to obtain proportions of the<br/>confirmed cases and patterns of anomalies.<br/><br/>Results: A total of 24 articles (11 case series, 9 case reports, and 4 others) were found to be eligible and included in this<br/>review. These articles reported 919 cases, with or without microcephaly, presumed to have congenital Zika virus infection. Of<br/>these cases, 884 (96.2%) had microcephaly. Of the 884 cases of microcephaly, 783 (88.6%) were tested for Zika virus infec-<br/>tion, and 216 (27.6%; 95% confidence interval, 24.5% to 30.8%) were confirmed to be Zika virus-positive. In addition to mi-<br/>crocephaly, other common abnormalities reported – out of 442 cases investigated – were calcifications of brain tissue (n=240,<br/>54.3%), ventriculomegaly (n=93, 20.8%), cerebellar hypoplasia (n=52, 11.7%), and ocular manifestations (n=46, 10.4%).<br/><br/>Conclusion: Based on the available literature, Zika virus infection during pregnancy might lead to a wide array of outcomes<br/>other than microcephaly. There is a need for more epidemiological studies in Zika-endemic areas, particularly in Africa, to<br/>ascertain the role of Zika virus in causing congenital neurological defects. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 23273 |
| 9 (RLIN) | 22970 |
| 9 (RLIN) | 15820 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="file:///C:/Users/CUHAS/Downloads/13-Article%20Text-26-1-10-20190622.pdf">file:///C:/Users/CUHAS/Downloads/13-Article%20Text-26-1-10-20190622.pdf</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | RESEARCH ARTICLES |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Date last seen | Copy number | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 11/22/2022 | 11/22/2022 | RA0815 | 11/22/2022 | RESEARCH ARTICLES |