Pattern, clinical characteristics, and outcome of meningitis among HIV-infected adults admitted in a tertiary hospital in North Western Tanzania: A cross-sectional study (Record no. 19573)

MARC details
000 -LEADER
fixed length control field 02612nam a22002777a 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240305193732.0
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fixed length control field 221122b |||||||| |||| 00| 0 eng d
028 ## - PUBLISHER OR DISTRIBUTOR NUMBER
Source Phone: +255 28 298 3384
Source Fax: +255 28 298 3386
Source Email: vc@bugando.ac.tz
Source Website: www.bugando.ac.tz
040 ## - CATALOGING SOURCE
Language of cataloging English
Transcribing agency DLC
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Matobogolo M Boaz
9 (RLIN) 45700
245 ## - TITLE STATEMENT
Title Pattern, clinical characteristics, and outcome of meningitis among HIV-infected adults admitted in a tertiary hospital in North Western Tanzania: A cross-sectional study
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. Hindawi &
-- Catholic University of Health and Allied Sciences [CUHAS – Bugando]
Date of publication, distribution, etc. 2016/8/29
490 ## - SERIES STATEMENT
Volume/sequential designation Journal of tropical medicine Volume 2016
520 ## - SUMMARY, ETC.
Summary, etc. Abstract:<br/><br/>Background: Limited information exists on the etiologies, clinical characteristics, and outcomes of meningitis among HIV-infected patients in Africa. We conducted a study to determine the etiology, clinical characteristics, and outcomes of meningitis among HIV-infected adults. <br/><br/>Methods: A prospective cross-sectional hospital based study was conducted among HIV-infected patients aged ≥18 years admitted to the medical wards with symptoms and signs of meningitis. Sociodemographic and clinical information were collected using a standardized data collection tool. Lumbar puncture was performed to all patients; cerebrospinal fluid samples were sent for analysis. <br/><br/>Results: Among 60 HIV-infected adults clinically diagnosed to have meningitis, 55 had CSF profiles consistent with meningitis. Of these, 14 (25.5%) had a laboratory-confirmed etiology while 41 (74.5%) had no isolate identified. Cryptococcus neoformans was the commonest cause of meningitis occurring in 11 (18.3%) of patients followed by Mycobacterium tuberculosis (6.7%). The in-hospital mortality was 20/55 (36.4%). Independent predictors of mortality were low baseline CD4 count and turbid CSF appearance. <br/><br/>Conclusion: Cryptococcal meningitis is the most prevalent laboratory-confirmed etiological agent among adult HIV-infected patients with suspected meningitis admitted to medical wards in Western Tanzania. Mortality rate in this population remains unacceptably high. Improving diagnostic capacity and early treatment may help to decrease the mortality rate.
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 22760
9 (RLIN) 23034
9 (RLIN) 45244
9 (RLIN) 15820
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1155/2016/6573672">https://doi.org/10.1155/2016/6573672</a>
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type RESEARCH ARTICLES
Holdings
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            MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO   11/22/2022   RA0781 11/22/2022 11/22/2022 RESEARCH ARTICLES
Catholic University of  Health and Allied Sciences - CUHAS
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