High oral carriage of non-albicans Candida spp. among HIV-infected individuals (Record no. 19536)
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000 -LEADER | |
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fixed length control field | 02531nam a22003257a 4500 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | OSt |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20240305193731.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 221121b |||||||| |||| 00| 0 eng d |
028 ## - PUBLISHER OR DISTRIBUTOR NUMBER | |
Source | Phone: +255 28 298 3384 |
Source | Fax: +255 28 298 3386 |
Source | Email: vc@bugando.ac.tz |
Source | Website: www.bugando.ac.tz |
040 ## - CATALOGING SOURCE | |
Language of cataloging | English |
Transcribing agency | DLC |
041 ## - LANGUAGE CODE | |
Language code of text/sound track or separate title | English |
100 ## - MAIN ENTRY--PERSONAL NAME | |
Personal name | Martha F Mushi |
9 (RLIN) | 19663 |
222 ## - KEY TITLE | |
Key title | Oral health non-Candida albicans Candida spp. HIV |
245 ## - TITLE STATEMENT | |
Title | High oral carriage of non-albicans Candida spp. among HIV-infected individuals |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Mwanza, Tanzania: |
Name of publisher, distributor, etc. | Elsevier & |
-- | Catholic University of Health and Allied Sciences [CUHAS – Bugando] |
Date of publication, distribution, etc. | 2016/8/1 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | Pages 185-188 |
490 ## - SERIES STATEMENT | |
Volume/sequential designation | International Journal of Infectious Diseases Volume 49 |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Abstract<br/><br/>Background: Non-albicans Candida (NAC) spp. in immunocompromised patients are linked to invasive infections with narrow treatment choice. This study aimed at comparing the oral colonization of NAC spp. between HIV and non-HIV infected individuals in Mwanza, Tanzania.<br/><br/>Method: Oral rinse of 351 HIV-infected and 639 non-HIV infected individuals were collected between March and July 2015. Phenotypic identifications of Candida spp. was done using Candida Chromogenic agar and confirmed by MALDI-TOF MS.<br/><br/>Results: NAC spp. were detected in 36/351 (10.3%) HIV-infected individuals compared to 28/639 (4.4%) of non-HIV infected individuals; P=0.0003. In HIV infected individuals, commonly isolated NAC spp. were Candida tropicalis, 10(2.8%), C. krusei (Issatschenki orientalis) 9(2.6%) and C. glabrata 8(2.3%). While for non-HIV infected individuals C. dubliniensis 8(1.3%) and C. tropicalis 5(0.9%) were commonly detected. As CD4 count/μl decreases by one unit the risk of being colonized by NAC spp. among HIV infected individuals increases by 1% (OR 1.01, 95% CI; 1.001-1.004, P=0.001).<br/><br/>Conclusion: The prevalence of NAC spp. is high among HIV-infected individuals with low CD4 count placing them at higher risk of invasive infections. Further studies to investigate the role of NAC spp. in causing invasive infections among immunocompromised patients are recommended. |
700 ## - ADDED ENTRY--PERSONAL NAME | |
9 (RLIN) | 23493 |
9 (RLIN) | 23714 |
9 (RLIN) | 45600 |
9 (RLIN) | 22927 |
9 (RLIN) | 23520 |
9 (RLIN) | 15820 |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="https://doi.org/10.1016/j.ijid.2016.07.001">https://doi.org/10.1016/j.ijid.2016.07.001</a> |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | ddc |
Koha item type | RESEARCH ARTICLES |
Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
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MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 11/21/2022 | RA0744 | 11/21/2022 | 11/21/2022 | RESEARCH ARTICLES |