Multicentre evaluation of significant bacteriuria among pregnant women in the cascade of referral healthcare system in North-Western Tanzania (Record no. 19426)

MARC details
000 -LEADER
fixed length control field 02827nam a22002897a 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240305193727.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 221115b |||||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Transcribing agency DLC
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name J Seni
9 (RLIN) 23416
245 ## - TITLE STATEMENT
Title Multicentre evaluation of significant bacteriuria among pregnant women in the cascade of referral healthcare system in North-Western Tanzania
Remainder of title bacterial pathogens, antimicrobial resistance profiles and predictors
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. Elsevier &
-- Catholic University of Health and Allied Sciences [CUHAS – Bugando]
Date of publication, distribution, etc. 2019/6/1
300 ## - PHYSICAL DESCRIPTION
Extent Pages 173-179
490 ## - SERIES STATEMENT
Volume/sequential designation Journal of Global Antimicrobial Resistance Volume 17
520 ## - SUMMARY, ETC.
Summary, etc. Abstract<br/><br/>Objectives: The aim of this multicentre study was to evaluate the magnitude of significant bacteriuria (SB) as well as the implicated bacterial pathogens, antimicrobial resistance (AMR) profiles and risk factors for SB among pregnant women attending different levels of healthcare facilities (HCFs) in Tanzania in order to guide antimicrobial therapy and preventive measures.<br/><br/>Methods: Information on sociodemographic and clinical characteristics, midstream urine culture and antimicrobial susceptibility testing was collected from 1828 pregnant women between March 2016 and May 2017. Data were analysed using STATA v.13.0 software.<br/><br/>Results: The prevalence of SB among pregnant women was 17.7% (323/1828; 95% CI 16.0–19.5%), with a predominance of Escherichia coli (164/323; 50.8%), Klebsiella spp. (55/323; 17.0%) and Staphylococcus aureus (28/323; 8.7%). Moreover, 37.5% (121/323) of bacteria were multidrug-resistant [84.3% (102/121) Gram-negative bacteria and 15.7% (19/121) in Gram-positive bacteria; P < 0.001]. Third-generation cephalosporin resistance in E. coli, Klebsiella spp. and other Enterobacteriaceae was 13.4%, 21.8% and 27.5%, respectively, and was higher in strains from a tertiary hospital (OR = 3.27, 95% CI 1.02–10.49; P = 0.046) compared with lower HCFs. Predictors of SB among pregnant women were lack of formal occupation, current hospital admission and presence of co-morbidities.<br/><br/>Conclusions: The prevalence of SB among pregnant women in this study was high (17.7%) and was within the same range reported 10 years ago in a single-centre baseline study. However, there is an increase in AMR in the cascade of referral healthcare system, underscoring the need for health facility level-specific antimicrobial stewardship.
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 45367
9 (RLIN) 45368
9 (RLIN) 23710
9 (RLIN) 45369
9 (RLIN) 23634
9 (RLIN) 45370
9 (RLIN) 23705
9 (RLIN) 23421
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1016/j.jgar.2018.12.024">https://doi.org/10.1016/j.jgar.2018.12.024</a>
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type RESEARCH ARTICLES
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Barcode Date last seen Price effective from Koha item type
            MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO   11/15/2022   RA0633 11/15/2022 11/15/2022 RESEARCH ARTICLES
Catholic University of  Health and Allied Sciences - CUHAS
Directorate of ICT @ 2024