Antimicrobial use across six referral hospitals in Tanzania (Record no. 19417)
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fixed length control field | 03465nam a22003497a 4500 |
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control field | OSt |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20240305193727.0 |
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fixed length control field | 221114b |||||||| |||| 00| 0 eng d |
028 ## - PUBLISHER OR DISTRIBUTOR NUMBER | |
Source | Phone: +255 28 298 3384 |
Source | Fax: +255 28 298 3386 |
Source | Email: vc@bugando.ac.tz |
Source | Website: www.bugando.ac.tz |
040 ## - CATALOGING SOURCE | |
Transcribing agency | DLC |
041 ## - LANGUAGE CODE | |
Language code of text/sound track or separate title | English |
100 ## - MAIN ENTRY--PERSONAL NAME | |
Personal name | Jeremiah Seni |
9 (RLIN) | 19633 |
245 ## - TITLE STATEMENT | |
Title | Antimicrobial use across six referral hospitals in Tanzania |
Remainder of title | A point prevalence survey |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Mwanza, Tanzania: |
Name of publisher, distributor, etc. | British Medical Journal Publishing Group & |
-- | Catholic University of Health and Allied Sciences [CUHAS – Bugando] |
Date of publication, distribution, etc. | 2020/12/1 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | Pages e042819 |
490 ## - SERIES STATEMENT | |
Volume/sequential designation | BMJ open Volume 10 Issue 12 |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Abstract<br/><br/>Objective: To delineate the prevalence and factors associated with antimicrobial use across six referral hospitals in Tanzania using WHO point prevalence survey (PPS) methodology to inform hospital-specific antimicrobial stewardship programmes.<br/><br/>Design: Cross-sectional analytical study.<br/><br/>Setting: Six referral hospitals in Tanzania.<br/><br/>Participants: Patients irrespective of age and gender (n=948) admitted in the six referral hospital wards before 8:00 hours on each day of the survey were included in December 2019. Using the WHO PPS methodology, data on hospitals, wards, patients, antibiotics, and indications for antibiotics were collected.<br/><br/>Outcome measures: We analysed the prevalence of antibiotic use by referral hospital, ward, indication and patient characteristics as the main outcomes. We also described adherence to the Tanzania Standard Treatment Guidelines (STG) and WHO’s AWaRe categorisation of antibiotics.<br/><br/>Results: Approximately 62.3% of inpatients were prescribed antibiotics, predominantly from the Access group of antibiotics (ceftriaxone, metronidazole or ampicillin–cloxacillin). The overall adherence of antibiotic prescriptions to the Tanzania STG was high (84.0%), with the exception of Sekou Toure Regional Referral Hospital (68.0%) and Maweni Regional Referral Hospital (57.8%). The most common indication for antibiotic prescriptions was community-acquired infections (39.8%). Children less than 2 years of age (OR 1.73, 95% CI 1.02 to 2.92, p=0.039); admission to surgical wards (OR 4.90, 95% CI 2.87 to 8.36, p <0.001); and admission to paediatric wards (OR 3.93, 95% CI 2.16 to 7.15, p <0.001) were associated with increased odds of antibiotic use. Only 2 of 591 patients were prescribed antibiotics based on culture and antimicrobial susceptibility testing results.<br/><br/>Conclusions: Empirical use of antibiotics is common, and the Access group of antibiotics is predominantly prescribed in children less than 2 years and patients admitted to surgical and paediatric wards. Lack of utilisation of antimicrobial susceptibility testing services in these hospitals requires urgent interventions. Routine monitoring of antibiotic use is recommended to be part of antibiotic stewardship programmes in Tanzania. |
700 ## - ADDED ENTRY--PERSONAL NAME | |
9 (RLIN) | 23367 |
9 (RLIN) | 23368 |
9 (RLIN) | 23369 |
9 (RLIN) | 23370 |
9 (RLIN) | 23371 |
9 (RLIN) | 23372 |
9 (RLIN) | 23373 |
9 (RLIN) | 23374 |
9 (RLIN) | 23375 |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="http://dx.doi.org/10.1136/bmjopen-2020-042819">http://dx.doi.org/10.1136/bmjopen-2020-042819</a> |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | ddc |
Koha item type | RESEARCH ARTICLES |
Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
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MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 11/14/2022 | RA0624 | 11/14/2022 | 11/14/2022 | RESEARCH ARTICLES |