The magnitude and correlates of Parvovirus B19 infection among pregnant women attending antenatal clinics in Mwanza, Tanzania (Record no. 19416)

MARC details
000 -LEADER
fixed length control field 03256nam a22003377a 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240305193727.0
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028 ## - PUBLISHER OR DISTRIBUTOR NUMBER
Source Phone: +255 28 298 3384
Source Fax: +255 28 298 3386
Source Email: vc@bugando.ac.tz
Source Website: www.bugando.ac.tz
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Transcribing agency DLC
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Mariam M Mirambo
9 (RLIN) 22927
222 ## - KEY TITLE
Key title Parvovirus B19 Pregnant women Tanzania
245 ## - TITLE STATEMENT
Title The magnitude and correlates of Parvovirus B19 infection among pregnant women attending antenatal clinics in Mwanza, Tanzania
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. BioMed Central &
-- Catholic University of Health and Allied Sciences [CUHAS – Bugando]
Date of publication, distribution, etc. 07 June 2017
300 ## - PHYSICAL DESCRIPTION
Extent Pages 1-7
490 ## - SERIES STATEMENT
Volume/sequential designation BMC pregnancy and childbirth Volume 17 Issue 1
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Summary, etc. Abstract<br/><br/>Background: Human parvovirus B19 (B19) infection has been associated with congenital infection which may result into a number of the adverse pregnancy outcomes. The epidemiology and the magnitude of B19 infections among pregnant women have been poorly studied in developing countries. This study was done to establish preliminary information about the magnitude of B19 among pregnant women attending antenatal clinics in the city of Mwanza, Tanzania.<br/><br/>Methods: A cross-sectional study was conducted between December 2014 and June 2015 among 258 pregnant women attending two antenatal clinics representing rural and urban areas in the city of Mwanza. Socio-demographic data were collected using structured data collection tool. Specific B19 IgM and IgG antibodies were determined using indirect enzyme linked immunosorbent assay kits (DRG Instruments GmbH, Germany). Data were analyzed using STATA version 11 software.<br/><br/>Results: The median age of study participants was 21 IQR (19–25) years. Of 253 pregnant women; 116(44.96%), 109(42.25%) and 33(12.79%) were in the first, second and third trimester respectively. The majority 168(66.4%) of women were from urban areas. Of 253 pregnant women, the overall prevalence of IgM was 83(32.8%) while that of IgG was 142(55.0%) among 258 women tested. A total of 50(19.4%) women were positive for both IgG and IgM indicating true IgM positive. History of baby with low birth weight (OR: 10, 95% CI: 1.82–58.05, P = 0.01) was independent predictor of B19 IgG seropositivity and being at the third trimester was protective (OR: 0.38, 95% CI: 0.16–0.92, P = 0.03). The IgG titers were found to decrease significantly as gestational age increases (Spearman’s rho = −0.2939, p = 0.0004)<br/><br/>Conclusion: More than a half of pregnant women in Mwanza city are B19 IgG sero-positive with about one third of these being B19 IgM seropositive. Further studies to determine the impact of B19 infections among pregnant women and their newborns are recommended in developing countries.
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9 (RLIN) 45318
9 (RLIN) 22970
9 (RLIN) 19663
9 (RLIN) 22727
9 (RLIN) 19633
9 (RLIN) 22780
9 (RLIN) 15820
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1186/s12884-017-1364-y">https://doi.org/10.1186/s12884-017-1364-y</a>
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type RESEARCH ARTICLES
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