Preliminary insights into the occurrence of similar clones of extended‐spectrum beta‐lactamase‐producing bacteria in humans, animals and the environment in Tanzania (Record no. 19413)

MARC details
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fixed length control field 02911nam a22003137a 4500
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control field OSt
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control field 20240305193726.0
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Source Phone: +255 28 298 3384
Source Fax: +255 28 298 3386
Source Email: vc@bugando.ac.tz
Source Website: www.bugando.ac.tz
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Transcribing agency DLC
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
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Personal name J Seni
9 (RLIN) 23416
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Title Preliminary insights into the occurrence of similar clones of extended‐spectrum beta‐lactamase‐producing bacteria in humans, animals and the environment in Tanzania
Remainder of title A systematic review and meta‐analysis between 2005 and 2016
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences [CUHAS – Bugando] &
-- Zoonoses and public health
Date of publication, distribution, etc. 22 August 2017
300 ## - PHYSICAL DESCRIPTION
Extent Pages 1-10
490 ## - SERIES STATEMENT
Volume/sequential designation Zoonoses and public health Volume 65 Issue 1
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Summary, etc. Summary<br/><br/>The emergence and spread of extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-PE) are complex and of the public health concern across the globe. This review aimed at assessing the ESBL-PE clones circulating in humans, animals and the environment to provide evidence-based insights for combating ESBL-PE using One Health approach. Systematic search from Medline/PubMed, Google Scholar and African Journals Online was carried out and retrieved nine eligible articles (of 131) based on phenotypic and genotypic detection of ESBL-PE between 2005 and 2016 in Tanzania. Analysis was performed using STATA 11.0 software to delineate the prevalence of ESBL-PE, phenotypic resistance profiles and clones circulating in the three interfaces. The overall prevalence of ESBL-PE in the three interfaces was 22.6% (95% CI: 21.1–24.2) with the predominance of Escherichia coli (E. coli) strains (51.6%). The majority of ESBL-PE were resistant to the commonly used antimicrobials such as trimethoprim–sulfamethoxazole and tetracycline/doxycycline, 38%–55% were resistant to ciprofloxacin and all were sensitive to meropenem/imipenem. ESBL-PE infections were more associated with deaths compared to non-ESBL-PE infections. Strikingly, E. coli ST38, ST131 and ST2852 were found to intersect variably across the three interfaces. The predominant allele, blaCTX-M-15, was found mostly in the conjugative IncF plasmids connoting transmission potential. The high prevalence of ESBL-PE and shared clones across the three interfaces, including the global E. coli ST131 clone, indicates wide and inter-compartmental spread that calls for One Health genomic-driven studies to track the resistome flow.<br/>
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9 (RLIN) 23339
9 (RLIN) 23633
9 (RLIN) 23634
9 (RLIN) 23421
9 (RLIN) 23705
9 (RLIN) 45315
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href=" https://doi.org/10.1111/zph.12387 "> https://doi.org/10.1111/zph.12387 </a>
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Source of classification or shelving scheme ddc
Koha item type RESEARCH ARTICLES
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