Prediction of Esophageal Candidiasis among Newly Diagnosed People Living with HIV at a Tertiary Hospital in Northwestern Tanzania (Record no. 19345)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03235nam a22003257a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240305193724.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 221110b |||||||| |||| 00| 0 eng d |
| 028 ## - PUBLISHER OR DISTRIBUTOR NUMBER | |
| Source | Phone: +255 28 298 3384 |
| Source | Fax: +255 28 298 3386 |
| Source | Email: vc@bugando.ac.tz |
| Source | Website: www.bugando.ac.tz |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | DLC |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Daniel W Gunda [RIP] |
| 9 (RLIN) | 22943 |
| 222 ## - KEY TITLE | |
| Key title | Endoscopy, esophageal candidiasis, HIV |
| 245 ## - TITLE STATEMENT | |
| Title | Prediction of Esophageal Candidiasis among Newly Diagnosed People Living with HIV at a Tertiary Hospital in Northwestern Tanzania |
| Remainder of title | A Cross Sectional Study |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza: |
| Name of publisher, distributor, etc. | Tanzania Medical Journal & |
| -- | Tanzania Catholic University of Health and Allied Sciences [CUHAS – Bugando] |
| Date of publication, distribution, etc. | 2022/1/31 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | Pages 1-15 |
| 490 ## - SERIES STATEMENT | |
| Volume/sequential designation | Tanzania Medical Journal Volume 33 Issue 1 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | <br/>Abstract<br/><br/><br/>Background: HIV infection causes a multisystem disease. Patients with upper gastrointestinal symptoms like dyspepsia, odynophagia, and dysphagia sometimes are usually treated empirically for esophageal candidiasis. Studies have suggested that a variety of other conditions may present with upper GIT and thus empirical treatment could potentially delay the institution of definitive treatment. This study describes endoscopic findings and prediction of esophageal candidiasis, which is an AIDS-defining illness among newly diagnosed people living with HIV at the Gastroenterology and hepatology unit at Bugando Tanzania.<br/><br/>Methods: A cross-section study was carried out among adult patients who presented at gastroenterology and hepatology unit for endoscopic service. All patients underwent HIV testing and counseling before the endoscope. Those who tested positive for HIV were serially enrolled in this study. Demographic, symptom profile, CD4 counts, and endoscopic findings were analyzed using STATA 13. The odds ratio (OR) with 95% Confidence Interval (CI) was calculated using univariate analysis followed by a multivariate analysis model to assess the extent of association. P value of <0.05 was considered as significant.<br/><br/>Results: In total 210 patients were enrolled in this study. The top three endoscopic findings were gastritis, 70 (33.3%; 95%CI: 26.9-39.7), esophageal candidiasis, 63 (30.0%; 95%CI: 23.8-36.2) and esophageal carcinoma, 28 (13.3%; 95%CI: 8.6-17.9). The presence of esophageal candidiasis was independently associated with Odynophagia, (OR: 6.1; 95%CI: 2.1-17.7; p=0.001), upper abdominal pain (OR: 2.3; 95%CI: 1.0-5.1, p=0.045) and CD4 count of less than 200cells/µL, (OR: 2.7; 95%CI: 1.3-5.3; p=0.005).<br/><br/>Conclusion: Esophageal candidiasis is prevalent in this study. Though Odynophagia, epigastric pains, and low CD4 counts can predict the presence of esophageal candidiasis, endoscopy is indicated for precise diagnosis of other conditions including esophageal carcinoma.<br/> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 22835 |
| 9 (RLIN) | 45199 |
| 9 (RLIN) | 22925 |
| 9 (RLIN) | 22926 |
| 9 (RLIN) | 45200 |
| 9 (RLIN) | 22704 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.4314/tmj.v33i1.413">https://doi.org/10.4314/tmj.v33i1.413</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | RESEARCH ARTICLES |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 11/10/2022 | RA0550 | 11/10/2022 | 11/10/2022 | RESEARCH ARTICLES |