Diagnostic Performance of Kato Katz Technique and Point-of-Care Circulating Cathodic Antigen Rapid Test in Diagnosing Schistosoma mansoni Infection in HIV-1 Co-Infected Adults on the Shoreline of Lake Victoria, Tanzania (Record no. 19306)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02904nam a22002657a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240305193722.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 221104b |||||||| |||| 00| 0 eng d |
| 028 ## - PUBLISHER OR DISTRIBUTOR NUMBER | |
| Source | Phone: +255 28 298 3384 |
| Source | Fax: +255 28 298 3386 |
| Source | Email: vc@bugando.ac.tz |
| Source | Website: www.bugando.ac.tz |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | DLC |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Humphrey D Mazigo |
| 9 (RLIN) | 22835 |
| 222 ## - KEY TITLE | |
| Key title | Schistosoma mansoni; HIV-1; point-of-care circulating cathodic antigen; sensitivity; specificity; adult; Tanzania |
| 245 ## - TITLE STATEMENT | |
| Title | Diagnostic Performance of Kato Katz Technique and Point-of-Care Circulating Cathodic Antigen Rapid Test in Diagnosing Schistosoma mansoni Infection in HIV-1 Co-Infected Adults on the Shoreline of Lake Victoria, Tanzania |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza: |
| Name of publisher, distributor, etc. | MDPI & |
| -- | Tanzania Catholic University of Health and Allied Sciences [CUHAS – Bugando] |
| Date of publication, distribution, etc. | 29 May 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | Pages 54 |
| 490 ## - SERIES STATEMENT | |
| Volume/sequential designation | Tropical medicine and infectious disease Volume 3 Issue 2 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract<br/><br/>Background: The diagnostic performance of the Kato Katz (KK) technique and the point-of-care circulating cathodic antigen (POC-CCA) test in detecting S. mansoni infection in the presence of the human immunodeficiency virus-1 (HIV-1) infection has remained inconclusive. The present cross-sectional survey compared the diagnostic performance of the KK technique and the POC-CCA test in diagnosing S. mansoni infection in an adult population co-infected with HIV-1 in northwestern Tanzania. <br/><br/>Methods: Single urine and stool samples from 979 adults were screened for S. mansoni infection using both the KK technique and POC-CCA tests. To compare the performance of the two diagnostic tests a combined artificial gold standard was created, based on either an egg-positive KK technique or a POC-CCA-positive test. <br/><br/>Results: Based on the KK technique, the prevalence of S. mansoni was 47.3% (463/979, 95% CI: 44.2–50.4), as compared to 60.5% by the POC-CCA test (592/979; 95% CI: 57.4–63.5). The overall sensitivity and specificity of the POC-CCA test were 92.5% (95% CI: 89.4–94.9) and 73.3% (95% CI: 69.6–76.8), respectively. In the HIV-1 seropositive group, the sensitivity and specificity of the POC-CCA test were 78.1% (95% CI: 60.0–90.7) and 45.9% (95% CI: 35.8–56.3). Using a combined gold standard, the sensitivity of the POC-CCA test increased to >90% in both subgroups whereas that of the KK technique in the HIV-1 seropositive group was low (49.5%; 95% CI: 39.6–59.5). <br/><br/>Conclusion: In the presence of HIV-1 co-infection, the KK technique attained a very low sensitivity. The POC-CCA test offers the best option for the rapid screening of S. mansoni infection in communities with a high prevalence of HIV-1 infection. <br/> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 23002 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.3390/tropicalmed3020054">https://doi.org/10.3390/tropicalmed3020054</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | RESEARCH ARTICLES |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 11/04/2022 | RA0511 | 11/04/2022 | 11/04/2022 | RESEARCH ARTICLES |