Manifestations of Tuberculosis in TB-HIV co-infected patients (Record no. 19202)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 03442nam a22003377a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240305193718.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 221031b |||||||| |||| 00| 0 eng d |
| 028 ## - PUBLISHER OR DISTRIBUTOR NUMBER | |
| Source | Phone: +255 28 298 3384 |
| Source | Fax: +255 28 298 3386 |
| Source | Email: vc@bugando.ac.tz |
| Source | Website: www.bugando.ac.tz |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | DLC |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mariam M Mirambo |
| 9 (RLIN) | 22927 |
| 222 ## - KEY TITLE | |
| Key title | Tuberculosis, HIV/AIDS, manifestations, opportunistic infections |
| 245 ## - TITLE STATEMENT | |
| Title | Manifestations of Tuberculosis in TB-HIV co-infected patients |
| Remainder of title | A retrospective study |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza: |
| Name of publisher, distributor, etc. | Tanzania Catholic University of Health and Allied Sciences [CUHAS – Bugando] |
| Date of publication, distribution, etc. | 2012/1/1 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | Pages 76-82 |
| 490 ## - SERIES STATEMENT | |
| Volume/sequential designation | Tanzania Med J Volume 26 Issue 2 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract<br/>Background: Tuberculosis (TB) is one of the common opportunistic infection and the main cause of death among HIV/AIDS patients. Diagnosis of TB in HIV/AIDS patients has been difficult due to atypical manifestations of TB in these patients<br/><br/>Broad objective: The main objective of the present study was to examine the common clinical and radiological manifestations of tuberculosis in association with immune status in HIV-TB co-infected patients<br/><br/>Methodology: Retrospective data of 339 HIV/AIDS patients co-infected with TB attended at Sekou Toure regional hospital between January 2007-May 2010 were collected. Information such as age, sex, baseline CD4 T cell counts, presented symptoms and form of TB were recorded and analyzed by Statistical package for social sciences (SPSS) version 17.0.<br/><br/>Results: Out of 339 patients, 165(48.7%) were females and 174 (51.3%) were males with mean age of 35 years. Of all the symptoms recorded, cough was the commonest symptom 320 (94.4%), recorded followed by weight loss 235(69.3%), fever 233(68.7%), night sweats 122(36%), anorexia 78(23%) and chest pain 27(8%) respectively. Radiological findings showed<br/>that pulmonary TB (PTB) was present in 310(91.4%) and extra pulmonary TB (EPTB) 48 (14.2%) patients respectively. Patients with both EPTB and PTB were 20(5.9%). Pleura effusion (50%) and adenitis (27%) were the common forms of EPTB. Acid fast bacilli results showed that, 112(33.04%) of the patients were AFB positive. Smear negativity rate was significantly high among patients with CD4 T cell count ≤ 400cells/μl (P=0.0001). Patients with TB symptoms and other clinical symptoms had significant low CD4 T cell counts (≤ 200 cells/μl) (P=0.0001).<br/><br/>Conclusions and recommendations: PTB with typical and atypical features was the most common manifestation of TB in HIV/AIDS co-infected patients. EPTB was also common and mostly in form of pleura effusion and adenitis. Low CD4 T cell counts were associated with high smear negativity rate and presence of other conditions in patients with TB symptoms. Sufficient knowledge of TB manifestation in HIV/AIDS patients is necessary for proper diagnosis of TB in HIV/AIDS patients. Moreover standardized diagnosis and optimization of case detection rate in HIV/AIDS needs to be adopted. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 44863 |
| 9 (RLIN) | 44864 |
| 9 (RLIN) | 44865 |
| 9 (RLIN) | 23053 |
| 9 (RLIN) | 44866 |
| 9 (RLIN) | 44848 |
| 9 (RLIN) | 22835 |
| 9 (RLIN) | 19663 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | RESEARCH ARTICLES |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 10/31/2022 | RA0401 | 10/31/2022 | 10/31/2022 | RESEARCH ARTICLES |