Complications of sickle cell anaemia in children in Northwestern Tanzania (Record no. 19017)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02614nam a22001937a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210826b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Hamza Saidi |
| 9 (RLIN) | 23697 |
| 245 ## - TITLE STATEMENT | |
| Title | Complications of sickle cell anaemia in children in Northwestern Tanzania |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences CUHAS - Bugando |
| Date of publication, distribution, etc. | 17 Feb 2016 |
| 490 ## - SERIES STATEMENT | |
| Materials specified | Hematology Volume 21, 2016 - Issue 4 |
| Series statement | Hematology Volume 21, 2016 - Issue 4 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract<br/><br/>Objectives: Tanzania has the third highest birth rate of sickle cell anaemia (SCA) in Africa, but few studies describe severity of complications or available treatments, especially in Northwest Tanzania around Lake Victoria where the sickle gene is most prevalent. This is a report of the spectrum of clinical disease and range of interventions available at Bugando Medical Centre (Bugando) in Northwest Tanzania in Africa.<br/><br/>Methods: A cross-sectional study was carried out in Bugando between 1 August 2012 and 30 September 2012. Children (<15 years old) with SCA attending Bugando were sequentially enrolled. A trained research assistant completed a Swahili questionnaire with the parent or guardian of each participant concerning demographic information, clinical features of disease, and treatments received.<br/><br/>Results: Among the 124 participants enrolled, the median age was 6 years (interquartile range [IQR] 4–8.5), and only 13 (10.5%) were < 3 years old. Almost all participants (97.6%) had a prior history of a vaso-occlusive episode, 83 (66.9%) had prior acute chest syndrome, and 21 (16.9%) had prior stroke. In the preceding 12 months, 120 (96.8%) had been hospitalized, and a vaso-occlusive episode was the most common reason for hospitalization (35.5%). Prescriptions for folic acid (92.7%) and malaria prophylaxis (84.7%) were common, but only one had received a pneumococcal vaccine, and none had received hydroxyurea or prophylactic penicillin.<br/><br/>Conclusion: Children with SCA receiving care in Tanzania are diagnosed late, hospitalized frequently, and have severe complications. Opportunities exist to improve care through wider access to screening and diagnosis as well as better coordination of comprehensive care.<br/><br/>Keywords: Sickle cell anaemia Tanzania Sub-Saharan Africa Vaso-occlusive episode Acute chest syndrome Stroke Children |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 23177 |
| 9 (RLIN) | 22814 |
| 9 (RLIN) | 22852 |
| 9 (RLIN) | 23698 |
| 9 (RLIN) | 22982 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Materials specified | https://doi.org/10.1080/10245332.2015.1101976 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | RESEARCH ARTICLES |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
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| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 08/26/2021 | RA0218 | 08/26/2021 | 08/26/2021 | RESEARCH ARTICLES |