The susceptibility of multidrug resistant and biofilm forming Klebsiella pneumoniae and Escherichia coli to antiseptic agents used for preoperative skin preparations at zonal referral hospital in Mwanza, Tanzania (Record no. 19016)
[ view plain ]
000 -LEADER | |
---|---|
fixed length control field | 02982nam a22001577a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 210826b |||||||| |||| 00| 0 eng d |
100 ## - MAIN ENTRY--PERSONAL NAME | |
Personal name | Prisca Damiano |
9 (RLIN) | 23691 |
245 ## - TITLE STATEMENT | |
Title | The susceptibility of multidrug resistant and biofilm forming Klebsiella pneumoniae and Escherichia coli to antiseptic agents used for preoperative skin preparations at zonal referral hospital in Mwanza, Tanzania |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Mwanza, Tanzania |
Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences CUHAS - Bugando |
Date of publication, distribution, etc. | March 2021 |
490 ## - SERIES STATEMENT | |
Materials specified | Malawi Medical Journal 33 (1); 59-64 March 2021Susceptibility of multidrug resistant and biofilm forming 59 |
Series statement | Malawi Medical Journal 33 (1); 59-64 March 2021Susceptibility of multidrug resistant and biofilm forming 59 |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Abstract<br/><br/>Background <br/><br/>Non-susceptibility of bacteria to antiseptic agents used for preoperative skin preparations threaten the effectiveness of prevention of surgical site infections. Data concerning susceptibility of multidrug resistant bacteria strains to antiseptic agents was limited at our <br/>setting. This study presents the susceptibility of extended spectrum β-lactamases producing Klebsiella pneumoniae and Escherichia coli <br/>(with and without biofilm formation) to antiseptic agents used for preoperative skin preparations at zonal referral hospital in Mwanza, <br/>Tanzania.<br/><br/>Methods <br/><br/>This cross-sectional descriptive study was conducted through July 2020. Presumptive extended spectrum beta-lactamase producing <br/>Klebsiella pneumoniae and Escherichia coli were recovered for this study. Disc combination method was used to confirm production of ESBL while tube method was used to detect biofilms formation. Then, isolates were tested for susceptibility towards 10% povidone iodine, 70% methylated spirit, 50% hydrogen peroxide (6% of industrial H2O2 diluted in equal volume with sterile distilled water) and <br/>2% chlorhexidine. STATA software version 13.0 was used for data analysis. <br/><br/>Results <br/><br/>A total of 31 presumptive ESBL producers were recovered and phenotypically confirmed, whereas 54.8% (n=17) were K. pneumoniae <br/>and 45.2% (n=14) were E. coli. Five (35.7%) E. coli and seven (41.2%) K. pneumoniae had positive biofilms test results. Four (12.9%) <br/>bacteria were non-susceptible to antiseptic agents used for preoperative skin preparations. However, none exhibited resistance towards <br/>10% PVP-I. <br/><br/>Conclusion <br/><br/>In this study we highlight the existence of multidrug resistant Gram-negative bacteria with resistance to antiseptic agents used for preoperative skin preparation at a zonal referral hospital in Mwanza, Tanzania.<br/>Keywords: antiseptic agents; biofilms; extended spectrum beta-lactamases; Escherichia coli; Klebsiella pneumoniae; multidrug resistance; surgical site infections. |
700 ## - ADDED ENTRY--PERSONAL NAME | |
9 (RLIN) | 23692 |
9 (RLIN) | 19665 |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
Materials specified | https://dx.doi.org/10.4314/mmj.v33i1.9 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | ddc |
Koha item type | RESEARCH ARTICLES |
Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 08/26/2021 | RA0217 | 08/26/2021 | 08/26/2021 | RESEARCH ARTICLES |