Prevalence of chronic kidney disease in diabetic adult out-patients in Tanzania (Record no. 19001)

MARC details
000 -LEADER
fixed length control field 02576nam a22002057a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210825b |||||||| |||| 00| 0 eng d
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Mubarakali N Janmohamed
9 (RLIN) 23619
245 ## - TITLE STATEMENT
Title Prevalence of chronic kidney disease in diabetic adult out-patients in Tanzania
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences CUHAS - Bugando
Date of publication, distribution, etc. 31 August 2013
490 ## - SERIES STATEMENT
Materials specified BMC Nephrology volume 14, Article number: 183 (2013)
Series statement BMC Nephrology volume 14, Article number: 183 (2013)
520 ## - SUMMARY, ETC.
Summary, etc. Abstract<br/><br/>Background<br/><br/>The number of adults with diabetes mellitus is increasing worldwide, particularly in Asia and Africa. In sub-Saharan Africa, renal complications of diabetes may go unrecognized due to limited diagnostic resources. The prevalence of chronic kidney disease (CKD) among adult diabetics in sub-Saharan Africa has not been well described.<br/><br/>Methods<br/><br/>This study was conducted at the diabetes mellitus clinic of Bugando Medical Centre in Mwanza, Tanzania. A total 369 consecutive adult diabetic patients were enrolled and interviewed. Each patient provided a urine sample for microalbuminuria and proteinuria and a blood sample for serum creatinine level. Estimated glomerular filtration rate (eGFR) was calculated using the Cockroft-Gault equation. CKD was staged according to the Kidney Disease Improving Global Outcomes system.<br/><br/>Results<br/><br/>A total of 309 (83.7%) study participants had CKD; 295 (80.0%) had significant albuminuria and 91 (24.7%) had eGFR < 60 ml/min. None of these patients were aware of their renal disease, and only 5 (1.3%) had a diagnosis of diabetic nephropathy recorded in their file. Older age was significantly associated with CKD in this population [OR 1.03, p = 0.03, 95%CI (1.00-1.05)].<br/><br/>Conclusions<br/><br/>Chronic kidney disease is highly prevalent among adult diabetic outpatients attending our clinic in Tanzania, but is usually undiagnosed. Nearly ¼ of patients had an eGFR low enough to require dose adjustment of diabetic medications. More diagnostic resources are needed for CKD screening among adults in Tanzania in order to slow progression and prevent complications.<br/><br/>Keywords<br/><br/>Diabetes mellitus; Microalbuminuria; Proteinuria; CKD; Chronic kidney disease; Sub-Saharan Africa
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 22747
9 (RLIN) 23020
9 (RLIN) 23057
9 (RLIN) 23177
9 (RLIN) 23034
9 (RLIN) 22982
856 ## - ELECTRONIC LOCATION AND ACCESS
Materials specified https://doi.org/10.1186/1471-2369-14-183
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type RESEARCH ARTICLES
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            MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO   08/25/2021   RA0202 08/25/2021 08/25/2021 RESEARCH ARTICLES
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