Multi-resistant gram negative enteric bacteria causing urinary tract infection among malnourished underfives admitted at a tertiary hospital, northwestern, Tanzania (Record no. 18999)

MARC details
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fixed length control field 03012nam a22002417a 4500
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100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Maimuna Ahmed
9 (RLIN) 23618
222 ## - KEY TITLE
Key title Malnourished; Underfives; UTI
245 ## - TITLE STATEMENT
Title Multi-resistant gram negative enteric bacteria causing urinary tract infection among malnourished underfives admitted at a tertiary hospital, northwestern, Tanzania
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences CUHAS - Bugando &
-- BioMed Central
Date of publication, distribution, etc. 19 June 2015
300 ## - PHYSICAL DESCRIPTION
Extent Pages 1-5
490 ## - SERIES STATEMENT
Materials specified Italian Journal of Pediatrics volume 41, Article number: 44 (2015)
Series statement Italian Journal of Pediatrics volume 41, Article number: 44 (2015)
Volume/sequential designation Journal Italian journal of pediatrics Volume 41 Issue 1
520 ## - SUMMARY, ETC.
Summary, etc. Abstract<br/><br/>Background: Infections are common complications occurring in malnourished childrenas a result of impaired immunity. Urinary tract infections (UTI) have been found to be the commonest cause of fever in normal children in developing countries. However, data regarding UTI among malnourished children is limited because in most of time severe and moderately malnourished children are afebrile despite significant bacteriuria.<br/><br/>Methods: A total of 402 malnourished underfives were enrolled. Demographic and other clinical characteristics were collected using standardized data collection tool. Urine specimens were cultured and interpreted according to standard operating procedures. Data were analyzed using STATA version 11.<br/><br/>Results: Out of 402 malnourished underfives, 229 (56.9 %) were male. The median age in months was 17 (IQR; 12–31). Of 402 malnourished underfives, 83 (20.3 %) had significant bacteriuria of gram negative enteric bacteria. Escherichia coli 35/84 and Klebsiella pneumonia 20/84 were predominant bacteria isolated. More than 37 % of isolates were resistant to third generation cephalosporins with all of them exhibiting extended spectrum beta lactamase (ESBL) phenotype. Rates of resistance to ampicillin, amoxillin/clavulanic acid, gentamicin and ciprofloxacin were 82/84 (98.7 %), 47/55 (85.4 %), 45/84 (57.8 %) and 9/84 (10.8 %) respectively. Decrease in age and increase in lymphocytes count were independent factors on multivariate logistic regression analysis found to predict UTI (p < 0.05).<br/><br/>Conclusions: Multi-resistant gram negative enteric bacteria are common cause of UTI among underfives. A significant number of severe and moderate malnourished children with bacteriuria had no fever. Therefore, routine testing for UTI is emphasized in all malnourished underfives so that appropriate treatment can be initiated.<br/><br/>
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 15820
9 (RLIN) 22814
9 (RLIN) 19633
9 (RLIN) 19663
9 (RLIN) 22795
9 (RLIN) 22927
9 (RLIN) 22727
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1186/s13052-015-0151-5">https://doi.org/10.1186/s13052-015-0151-5</a>
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type RESEARCH ARTICLES
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