Infantile hypertrophic pyloric stenosis at a tertiary care hospital in Tanzania: a surgical experience with 102 patients over a 5-year period (Record no. 18962)

MARC details
000 -LEADER
fixed length control field 02946nam a22002177a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1756-0500
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Phillipo L. Chalya
9 (RLIN) 15821
222 ## - KEY TITLE
Key title Infantile hypertrophic pyloric stenosis Treatment Outcome Tanzania
245 ## - TITLE STATEMENT
Title Infantile hypertrophic pyloric stenosis at a tertiary care hospital in Tanzania: a surgical experience with 102 patients over a 5-year period
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences CUHAS - Bugando &
-- BioMed Central
Date of publication, distribution, etc. 18 November 2015
300 ## - PHYSICAL DESCRIPTION
Extent Pages 1-6
490 ## - SERIES STATEMENT
Volume/sequential designation BMC research notes Volume 8 Issue 1
520 ## - SUMMARY, ETC.
Summary, etc. Abstract:<br/><br/>Background: Infantile hypertrophic pyloric stenosis (IHPS) is the most common cause of gastric outlet obstruction in infants. There is paucity of published data regarding this condition in our setting. This study describes the clinical presentation, mode of treatment and outcome of treatment of this disease and identifies factors responsible for poor outcome of these patients.<br/><br/>Methods: This was a descriptive retrospective study of infants with HPS admitted to Bugando Medical Centre and subsequently underwent surgery between February 2009 and January 2014.<br/><br/>Results: A total of 102 patients (M:F = 4.7:1) were studied. The median age at presentation was 5 weeks. The median duration of illness was 4 weeks. Fifty-four (52.9 %) patients occur in first-born children. Associated anomalies were reported in 7 (6.9 %) patients. Non-bilious vomiting was the most frequent symptom and it was described in all (100 %) patients. A palpable mass was found in 23.5 % of infants. The diagnosis of IHPS was made clinically in 86 (84.3 %) and by ultrasound in 16 (15.7 %) patients. The treatment was Ramstedt’s pyloromyotomy in all cases. There were 6 (5.9 %) intra-operative mucosal perforations which were repaired successively. Postoperative complication was 11.8 %. The median length of hospital stay was 12 days and it was significantly associated with prolonged pre-operative hospitalization (p = 0.001). The mortality rate was 4.9 %. Age below 2 weeks, late presentation (≥14 days), severe dehydration on admission, hypokalaemia on admission and surgical site infection were the main predictors of mortality (p < 0.001).<br/><br/>Conclusion: This study has shown that IHPS is a common condition in our setting. Age <2 weeks, delayed presentation, prolonged preoperative hospital stay, surgical site infection and high proportion of dehydration and electrolyte disturbance were the main predictors of poor outcome. A high index of suspicion is needed in infants with non-bilious vomiting to avoid delay in diagnosis.
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 20085
9 (RLIN) 22934
9 (RLIN) 22948
9 (RLIN) 23352
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1186/s13104-015-1660-4">https://doi.org/10.1186/s13104-015-1660-4</a>
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type RESEARCH ARTICLES
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