Hypertension Is a Key Feature of the Metabolic Syndrome in Subjects Aging with HIV (Record no. 18854)

MARC details
000 -LEADER
fixed length control field 02539nam a22001937a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Raquel Martin-Iguacel
9 (RLIN) 46645
222 ## - KEY TITLE
Key title Keywords Metabolic syndrome Antiretroviral therapy Cardiovascular risk HIV infection Hypertension
245 ## - TITLE STATEMENT
Title Hypertension Is a Key Feature of the Metabolic Syndrome in Subjects Aging with HIV
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences CUHAS - Bugando &
-- Springer US
Date of publication, distribution, etc. 30 April 2016
300 ## - PHYSICAL DESCRIPTION
Extent Pages 1-14
490 ## - SERIES STATEMENT
Series statement Martin-Iguacel, R., Negredo, E., Peck, R. et al. Hypertension Is a Key Feature of the Metabolic Syndrome in Subjects Aging with HIV. Curr Hypertens Rep 18, 46 (2016). https://doi.org/10.1007/s11906-016-0656-3
520 ## - SUMMARY, ETC.
Summary, etc. Abstract<br/><br/>With widespread and effective antiretroviral therapy, the life expectancy in the HIV population has dramatically improved over the last two decades. Consequently, as patients are aging with HIV, other age-related comorbidities, such as metabolic disturbances and cardiovascular disease (CVD), have emerged as important causes of morbidity and mortality. An overrepresentation of traditional cardiovascular risk factors (RF), toxicities associated with long exposure to antiretroviral therapy, together with residual chronic inflammation and immune activation associated with HIV infection are thought to predispose to these metabolic complications and to the excess risk of CVD observed in the HIV population. The metabolic syndrome (MS) represents a clustering of RF for CVD that includes abdominal obesity, hypertension, dyslipidemia and insulin resistance. Hypertension is a prevalent feature of the MS in HIV, in particular in the aging population, and constitutes an important RF for CVD. Physicians should screen their patients for metabolic and cardiovascular risk at the regular visits to reduce MS and the associated CVD risk among people aging with HIV, since many of RF are under-diagnosed and under-treated conditions. Interventions to reduce these RF can include lifestyle changes and pharmacological interventions such as antihypertensive and lipid-lowering therapy, and treatment of glucose metabolism disturbances. Changes in antiretroviral therapy to more metabolic neutral antiretroviral drugs may also be considered.
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 46646
9 (RLIN) 22817
9 (RLIN) 46647
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1007/s11906-016-0656-3">https://doi.org/10.1007/s11906-016-0656-3</a>
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type RESEARCH ARTICLES
Holdings
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Catholic University of  Health and Allied Sciences - CUHAS
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