The Prevalence and Factors Associated With Left Atrial Abnormalities among Stroke Patients and 30-Day Outcomes of Stroke Patients Admitted At Bugando Medical Centre and Sekou Toure Regional Referral Hospital (Record no. 18783)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04401nam a22003137a 4500 |
| 001 - CONTROL NUMBER | |
| control field | CUHAS/MMED/6000387/T/20 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | CUHAS/MMED/6000387/T/20 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240424162916.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 231123b |||||||| |||| 00| 0 eng d |
| 028 ## - PUBLISHER OR DISTRIBUTOR NUMBER | |
| Source | Wurzburg Road 35, BMC Premises, Post Code: 33102: |
| Source | P. O. Box 1464, Mwanza – Tanzania: |
| Source | Phone: +255 28 298 3384: |
| Source | Fax: +255 28 298 3386: |
| Source | Email: vc@bugando.ac.tz: |
| Source | www.bugando.ac.tz |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | CUHAS/MMED/6000387/T/20 |
| 040 ## - CATALOGING SOURCE | |
| Language of cataloging | English |
| Transcribing agency | DDC |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mlagwa Lucas Yango |
| Dates associated with a name | [Male] |
| Relator term | CUHAS/MMED/6000387/T/20 |
| 245 ## - TITLE STATEMENT | |
| Title | The Prevalence and Factors Associated With Left Atrial Abnormalities among Stroke Patients and 30-Day Outcomes of Stroke Patients Admitted At Bugando Medical Centre and Sekou Toure Regional Referral Hospital |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania: |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences [CUHAS – Bugando] : |
| Date of publication, distribution, etc. | 2023 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 120 Pages |
| Extent | Includes References and Appendices |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | <br/>Abstract: <br/><br/>Background: Left atrial abnormality (LAA) is associated with an increased risk of developing stroke and atrial fibrillation, a known risk factor for stroke. Left atrial abnormalities have been proposed to be potential identifiers for developing stroke and atrial fibrillation, particularly paroxysmal atrial fibrillation (PAF) especially those in sinus rhythm. There is limited data on the magnitude of LAA among stroke patients and the factors associated with LAA among stroke patients.<br/><br/>Objective. To determine the prevalence and associated factors with LAA and 30-day outcomes of stroke patients admitted at Bugando Medical Center and Sekoutoure Regional Referral Hospital.<br/><br/>Methodology. This was a mixed study design (cross-sectional and prospective cohort) that was conducted between October 2022 to April 2023. Consecutive stroke patients aged≥18years were enrolled in the study. A structured questionnaire was used to collect the demographics and clinical characteristics of the patients. A non-contrast computed tomography head was performed on all patients to determine the type of stroke and cardiovascular assessment (electrocardiogram and echocardiogram) to detect the presence of left atrial abnormality. Each participant was followed up for 30 days to determine outcomes. Logistic regression was used to examine baseline factors associated with LAA and Kaplan-Meier analysis was used to describe survival probabilities between the two groups.<br/><br/>Results: 405 patients were enrolled, 62.72% were male with a mean age of 65.35±15.2 years, and 91.11% had a history of hypertension. The prevalence of LAA by ECHO and/or ECG was 51.11% among these 19.26% had any ECG LAA and 42.22% had any ECHO LAA. The most common pattern of ECG LAA observed was beat-to-beat p-wave variation and the only pattern of ECHO LAA observed was LAE. Factors associated with LAA were atrial fibrillation (aOR=12,95%CI 4.1-35.3, p-value <0.001), left ventricular hypertrophy (aOR=1.9,95%CI 1.05-3.53, p-value 0.042), dilated cardiomyopathy (aOR=47,95% CI 15.2-148.3, p-value <0.001), age > 60 yrs. (aOR=1.6,95% CI 1.02-2.6, p-value 0.039) and ischemic stroke (aOR=7.1,95%CI 03.7-13.79, pvalue <0.001). The overall mortality was 25.56% among these 62.13% had LAA. Factors associated with mortality were LAA (aOR 3.7 (95% CI 1.74-7.91), p-value <0.001), ischemic stroke (aOR 0.35 (95% CI 0.16-0.734) p-value 0.006), left ventricular hypertrophy (aOR 1.9 (95%CI 1.02-3.52), p-value 0.042), moderate and severe stroke (aOR=3.12 (95% CI 2.04-4.74), p-value <0.001), and a Glasgow coma score of >9 (aOR=0.42 (95%CI 0.24-0.74), p-value <0.003).<br/><br/>Conclusions and recommendations: There prevalence of LAA is high, coupled with high mortality at 30 days. The factors associated with LAA were modifiable risk factors and predictors of mortality. The predictors of mortality were the presence of LAA, hemorrhagic stroke, and severe stroke with neurologic impairment. Therefore, we recommend early screening, treatment, and control of risk factors for LAA and stroke and the urgent need of promoting pragmatic interventions to reduce morbidity and mortality from stroke.<br/> |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Internal Medicine |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | POSTGRADUATE DISSERTATIONS |
| Suppress in OPAC | |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 11/23/2023 | CUHAS/MMED/6000387/T | 11/23/2023 | 11/23/2023 | POSTGRADUATE DISSERTATIONS |