Factors Associated with Colonization of Streptococcus Pneumoniae Among Under-Fives Attending Reproductive and Child Health Clinics in Mwanza City, Tanzania. (Record no. 18704)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03569nam a22002897a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240305193657.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 230213b |||||||| |||| 00| 0 eng d |
| 028 ## - PUBLISHER OR DISTRIBUTOR NUMBER | |
| Source | Phone: +255 28 298 3384 |
| Source | Fax: +255 28 298 3386 |
| Source | Email: vc@bugando.ac.tz |
| Source | Website: www.bugando.ac.tz |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | DLC |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| Language code of text/sound track or separate title | Kiswahili |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Apansia Jonathan Ndossa |
| 9 (RLIN) | 48375 |
| 245 ## - TITLE STATEMENT | |
| Title | Factors Associated with Colonization of Streptococcus Pneumoniae Among Under-Fives Attending Reproductive and Child Health Clinics in Mwanza City, Tanzania. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania: |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences [CUHAS – Bugando] |
| Date of publication, distribution, etc. | c2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 50 Pages |
| Extent | Includes References and Appendices |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract: <br/><br/>Background: Streptococcus pneumonia is a known cause of severe invasive bacterial infection leading to morbidity and mortality among children in sub-Saharan Africa. Nasopharyngeal colonization of S. pneumonia is a critical step towards invasive progression. This study was done to determine the prevalence of nasopharyngeal carriage of S. pneumonia and possible factors associated with the carriage. In addition the susceptibility pattern of isolates to commonly used antibiotics was investigated.<br/><br/>Methods: A total of 350 under-fives attending RCH clinics in Mwanza city were enrolled and investigated for nasopharyngeal carriage of S. pneumonia. Demographic and clinical data were collected using standardized data collection tool. Nasopharyngeal swabs were taken and processed as per standard laboratory procedures. S. pneumonia isolates were identified using conventional methods. Antimicrobial susceptibility testing was performed using the disc diffusion method as described by clinical laboratory standard institute (CLSI)<br/><br/>Results: Of 350 children; 309(88.1%) were under 2years of age while only 11(3.1%) of children were at school. Two hundred and fifty three children (72.3%) had received at least one dose pneumococcal vaccine whereas 83(23.7%) had used antibiotics at median duration of 5 days in the past 14 days. Out of 350 under-fives, 43(12.3%) were found to carry S. pneumonia in their Nasopharynx. Children with chronic diseases and those at school were 3.4 and 4.4 times more risk to be carries of S. pneumonia than their counterpart group (OR; 3.4; 95% CI [1.0-11.6]; p-value 0.05) and (OR; 4.4; 95% CI [1.2-15.7] p-value 0.023) respectively. Number of children at home, positive HIV status and someone smoking showed association with S. pneumonia carriage but the differences were not statistically significant. The resistance levels of S. pneumonia to penicillin, co-trimoxazole and erythromycin were 40%, 88.2% and 41.7% respectively however all of the S. pneumonia isolates were found to be 100% sensitive to ciprofloxacin.<br/><br/>Conclusion: A high nasopharyngeal carriage of penicillin resistant S. pneumoniae is observed in Mwanza, Tanzania despite a good coverage of pneumococcal vaccination. The carriage if significantly associated with schooling, symptoms of upper respiratory tract infections and presence of chronic diseases. Continuous surveillance of penicillin resistant strains coupled with serotyping of the isolates is highly recommended to determine the influence of the pneumococcal vaccination.<br/> |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Paediatrics and Child Health |
| 9 (RLIN) | 33433 |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 22795 |
| 9 (RLIN) | 15820 |
| 9 (RLIN) | 22050 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | POSTGRADUATE DISSERTATIONS |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 02/13/2023 | CREC/412023 | 02/13/2023 | 02/13/2023 | POSTGRADUATE DISSERTATIONS |