Incidence, Predictors and Outcome of Venous Thromboembolism Among Patients Undergoing Major Operation at Bugando Medical Centre. Mwanza, Tanzania (Record no. 18522)

MARC details
000 -LEADER
fixed length control field 06715nam a22004097a 4500
001 - CONTROL NUMBER
control field CUHAS/MMED/6000225/T/16
003 - CONTROL NUMBER IDENTIFIER
control field CUHAS/MMED/6000225/T/16
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240422143401.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210821b |||||||| |||| 00| 0 eng d
028 ## - PUBLISHER OR DISTRIBUTOR NUMBER
Source Wurzburg Road 35, BMC Premises, Post Code: 33102:
Source P. O Box 1464, Mwanza – Tanzania:
Source Phone: +255 28 298 3384:
Source Fax: +255 28 298 3386:
Source Email: vc@bugando.ac.tz :
Source Website: www.bugando.ac.tz
035 ## - SYSTEM CONTROL NUMBER
System control number CUHAS/MMED/6000225/T/16
040 ## - CATALOGING SOURCE
Language of cataloging English
Transcribing agency ddc
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Allen Gabriel Kangalawe
Dates associated with a name [Male]
9 (RLIN) 22853
Relator term CUHAS/MMED/6000225/T/16
210 ## - ABBREVIATED TITLE
Abbreviated title ABBREVIATIONS
Qualifying information AIDS Acquired Immunodeficiency Syndrome ASA American Association of Anesthesiologist BMC Bugando Medical Centre BMI Body Mass Index CREC CUHAS-BMC Research and Ethics Committee CTPA Computerized Tomography Pulmonary Angiography CUHAS Catholic University of Health and Allied Science CVD Cardiovascular Disease CXR Chest X-Ray DM Diabetes Mellitus DUS Doppler Ultrasonography DVT Deep Venous Thrombosis ECG Electrocardiogram EMD Emergency Medicine Department ENT Ear Nose and Throat GOPD Gynecological Outpatients Department HIV Human Immunodeficiency Virus IQR Interquartile Range LMWH Low Molecular Weight Heparin MOPD Medical Outpatients Department PE Pulmonary Embolism PI Principle Investigator SOPD Surgical Outpatients Department STATA South Texas Art Therapy Association UFH Unfractionated heparin US United States VTE Venous Thromboembolism
222 ## - KEY TITLE
Key title OPERATIONAL DEFINITIONS For the purposes of this study the following were defined as follows:-
Qualifying information Outcome of surgery: was defined as patients with radiological and/or clinical evidence VTE (i.e. DVT or PE or both) and death following a major surgery.
Key title OPERATIONAL DEFINITIONS For the purposes of this study the following were defined as follows:-
Qualifying information Duration of surgery: Is the total time between (cutting time) knife to skin, to the closure of skin, and for endoscopic surgery is the time duration from introduction of scope to the patient and removal of scope from the patient after completing the surgery
Key title OPERATIONAL DEFINITIONS For the purposes of this study the following were defined as follows:-
Qualifying information Major surgery/operation: Is any open or laparoscopic intervention occurring in operating theatre requiring regional or general anaesthesia lasting more than 45minutes associated with an expected blood loss >500mls, at least one night of admission in hospital, opening of body cavity, resection of organ, extensive soft tissue resection or manipulation, joint replacement, open reduction and internal fixation and spine, thoracic, vascular or intracranial surgery.
Key title OPERATIONAL DEFINITIONS For the purposes of this study the following were defined as follows:-
Qualifying information Pulmonary embolism: Is a dislodged blood clot from the deep veins in the lower extremities or pelvis which travels through the circulation and lodges into the pulmonary vessels and manifest with chest pain, difficulty in breathing, coughing +/-blood, fast breathing and heart rate, low blood pressure and fever occurring within 4 weeks or more after major operation.
Key title OPERATIONAL DEFINITIONS For the purposes of this study the following were defined as follows:-
Qualifying information Deep vein thrombosis: Is a clinical and/or radiological presentation of the clotted blood in the deep veins of the lower extremities or pelvis occurring within 4 weeks or more following a major operation and manifest with unilateral or bilateral lower limb swelling, pain, tenderness, warm skin and bluish or reddish skin coloration around the affected area.
Key title OPERATIONAL DEFINITIONS For the purposes of this study the following were defined as follows:-
Qualifying information Venous thromboembolism: Is a clinical and/or radiological presentation of the clotted blood in the deep veins of the lower extremities or pelvis with or without pulmonary manifestation, occurring within 4 weeks or more following a major operation.
245 ## - TITLE STATEMENT
Title Incidence, Predictors and Outcome of Venous Thromboembolism Among Patients Undergoing Major Operation at Bugando Medical Centre. Mwanza, Tanzania
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania:
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences [CUHAS - Bugando] :
Date of publication, distribution, etc. 2020
300 ## - PHYSICAL DESCRIPTION
Extent xii; 87 Pages
Extent Includes References and Appendices
520 ## - SUMMARY, ETC.
Summary, etc. Abstract:<br/><br/>Background: Venous thromboembolism (VTE) is a disorder that includes deep venous thrombosis and pulmonary embolism. This study aimed to determine the incidence, predictors, and outcome of venous thromboembolism among patients undergoing major operations at Bugando Medical Centre. <br/><br/>Methods: Longitudinal study was conducted in the department of surgery at Bugando Medical Centre from February to July 2020. We recruited 400 patients undergoing major surgery, all study participants were screened for VTE using modified Caprini for DVT and modified Wells score for PE. Patients with high score from Caprini and Wells score were subjected to doppler ultrasonography and computerized tomography pulmonary angiography to confirm the diagnosis. Patient who had sudden death prior to these investigations underwent postmortem to confirm the diagnosis. Data were analyzed using STATA version 13.A p-value of <0.05 was significant <br/><br/>Results: The cumulative incidence of VTE was 11.8% with median age of 38 [IQR, 28-61] years. Age ≥45 years, body mass index ≥25, hypertension and prolonged duration of immobilization were the main predictors of VTE. Among 381 patients’ (43.0%, n=164) patients were postoperatively classified as having a high risk of developing VTE. Of these, (27.7%, n=45) developed VTE (fisher’s exact p<0.001). Out of 45 patients with VTE, 14 patients’ died resulting in a mortality rate of 31.1%. Mortality was associated with male gender (X2=6.1329, P=0.013). Only (17.7%, n=29) of high-risk patients received VTE prophylaxis, however, prophylaxis was protective against development of VTE (fisher exact P=0.023) which was statistically significant. <br/><br/>Conclusion: The study has demonstrated that VTE is not uncommon among postoperative patients at BMC and is associated with high mortality rate. At Bugando Medical Center, VTE prophylaxis is significantly underutilized. Therefore, implementation of appropriate prophylaxis measures to all patients at risk of developing VTE is of paramount importance in order to lower the risk of VTE.<br/>
600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME
General subdivision Surgery
9 (RLIN) 29082
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 19950
9 (RLIN) 20966
9 (RLIN) 22736
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type POSTGRADUATE DISSERTATIONS
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Barcode Date last seen Price effective from Koha item type
            MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO   08/21/2021   PD0383 08/21/2021 08/21/2021 POSTGRADUATE DISSERTATIONS
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