Clinical Profile and Outcomes of Patients With Clinical Benign Prostate Hyperplasia Treated by Trans Urethral Resection of Prostate at at Bugando Medical Centre, Mwanza Tanzania. (Record no. 18457)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 06346nam a22003977a 4500 |
| 001 - CONTROL NUMBER | |
| control field | CUHAS/MMED/6000214/T/16 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | CUHAS/MMED/6000214/T/16 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240419113023.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210821b |||||||| |||| 00| 0 eng d |
| 028 ## - PUBLISHER OR DISTRIBUTOR NUMBER | |
| Source | Wurzburg Road 35, BMC Premises, Post Code: 33102: |
| Source | P. O Box 1464, Mwanza – Tanzania: |
| Source | Phone: +255 28 298 3384: |
| Source | Fax: +255 28 298 3386: |
| Source | Email: vc@bugando.ac.tz : |
| Source | www.bugando.ac.tz |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | CUHAS/MMED/6000214/T/16 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | ddc |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | George Mocha |
| Dates associated with a name | [Male] |
| 9 (RLIN) | 22743 |
| Relator term | CUHAS/MMED/6000214/T/16 |
| 210 ## - ABBREVIATED TITLE | |
| Abbreviated title | LIST OF ABBREVIATIONS |
| Qualifying information | AKI Acute Kidney Injury BMC Bugando Medical Center. BPH Benign Prostate Hyperplasia. B-TURP Bipolar Transurethral Resection of Prostate CKD Chronic Kidney Disease CKD-EPI Chronic Kidney Disease Epidemiology collaboration. CUHAS Catholic University of Health and allied sciences. DHT Dihydrotestosterone FGF-2 Fibroblast Growth Factor 2 IL-8 Interleukin -8 IPSS International Prostate Symptom Score LUTS Lower Urinary Tract Symptoms M-TURP Monopolar Transurethral Resection of Prostate PVR Post-Voidal Residual urine volume Qmax Maximum flow rate TAUS Trans Abdominal Ultrasound TUMT Trans Urethral Microwave Thermotherapy TUNA Trans Urethral Needle Ablation TURP Trans Urethral Resection of Prostate TUVP Transurethral Vaporization of the Prostate USS Ultrasound UTI Urinary Tract Infection |
| 222 ## - KEY TITLE | |
| Key title | DEFINITION OF TERMS As far as this study is concerned |
| Key title | DEFINITION OF TERMS As far as this study is concerned |
| Qualifying information | Clinical BPH; Refers to patients with symptoms and sign suggestive of prostatic obstructions but with no histological confirmation of BPH yet. |
| Key title | DEFINITION OF TERMS As far as this study is concerned |
| Qualifying information | Outcomes: Means improvement of symptoms as measured by IPSS and QoL, of which it will be favorable if the IPSS score on follow up decreased to <7 or decrease of pre op score by >50% and improvement of QoL score to <3. |
| Key title | DEFINITION OF TERMS As far as this study is concerned |
| Qualifying information | Perioperative complications; complications extending from intraoperative to throught hospital stay. |
| Key title | DEFINITION OF TERMS As far as this study is concerned |
| Qualifying information | Early TURP complications: These refer to any untoward outcome as a result of the procedure either intraoperative, or post-operative (that is before discharge and during the follow up period of 3months.) |
| 245 ## - TITLE STATEMENT | |
| Title | Clinical Profile and Outcomes of Patients With Clinical Benign Prostate Hyperplasia Treated by Trans Urethral Resection of Prostate at at Bugando Medical Centre, Mwanza Tanzania. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania: |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences [CUHAS - Bugando] : |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | xii; 64 Pages |
| Extent | Includes References and Appendices |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract:<br/><br/>Background: Benign prostate hyperplasia (BPH) is the most common prostate pathology in elderly men. Trans Urethral Resection of the Prostate (TURP) is still considered as the gold standard surgical management of BPH. TURP is the commonest endoscopic surgery performed for BPH in developing countries including Tanzania, however its outcome is not known. This study determined the clinical profile, outcome as well as predictors of outcome in patients with clinical BPH undergoing TURP at Bugando Medical Centre (BMC), a tertiary hospital in Mwanza, Tanzania.<br/><br/>Methods: This was a cross sectional longitudinal hospital based study to evaluate the clinical profile as well as the outcome of patients with clinical BPH treated by TURP at Bugando Medical Centre from November 2018 to April 2019. All participants with clinical BPH and scheduled for TURP and consented for the study were included, their international prostate symptom score (IPSS) with the 8th question for quality of life (QoL) was scored, their age, residence, renal status, PSA, size of the prostate, urinalysis as well as urine culture were recorded. They were admitted and prepared for the operation. Intraoperatively, experience of the surgeon, duration, weight of resected prostate, and complication/s were recorded. Progress in the ward was recorded and following discharge patient was scheduled for follow up at 6 and 12 weeks. During follow up, IPSS and QoL scores as well as complication was reported. Patients were deemed improved if follow up IPSS was either ≤7 or decreased by ≥50% and QoL score is <3. Univariate and multivariate logistic regressions were used to identify factors, which affects improvement of symptoms.<br/><br/>Results: A total of 210 participants met the inclusion criteria. The median age was 69 (IQR 63 – 75) years. Prostate size ranged from 15 – 200grams with median size of 77 (IQR 51 – 107) mls. Acute urine retention was the most common indication 69 (33%), followed by lower urinary tract symptoms 52 (25%). Urologist operated most of the patient 122 (58.1%) with the rest operated by either resident alone or finished up by urologist, and the median weight resected was 20 (IQR 13.5 – 28.3) grams. About 66 (31.4%) developed perioperative complication with majority having clot retention. During follow up, the median IPSS score was 9 (IQR 7 – 12) and 2 (IQR 0 – 6) and median QoL score of 3 (IQR 1 – 3) and 0 (IQR 0 – 1) with improvement in 93 (45.4%) and 184 (89.8%) on 1st and 2nd visits respectively. There were a total of 9 (4.3%) patients whom developed Tran’s urethral resection (TUR) syndrome out of which 1 (11.1%) died and overall mortality was 3 (1.4%) participants.<br/><br/>Conclusion: BPH is common from 6th decade of life onwards. Though most participants were operated because of either acute urine retention or disturbing LUTS, some presents late already with renal insufficiency. Despite the fact the most of the participants had severe symptoms and their quality of life was poor at presentation, TURP improved symptoms in most of the participants. The improvement is even better in the hands of experienced surgeon, for the participants with small prostate and in absence of UTI prior to surgery. <br/> |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Medicine in Urology |
| 9 (RLIN) | 48296 |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 19950 |
| 9 (RLIN) | 19776 |
| 9 (RLIN) | 19763 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | POSTGRADUATE DISSERTATIONS |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 08/21/2021 | PD0318 | 08/21/2021 | 08/21/2021 | POSTGRADUATE DISSERTATIONS |