Inhaled sedation in the (Record no. 13873)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04061nam a22001577a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210521b |||||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783658273514 |
| International Standard Book Number | 9783658273521 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Andreas Meiser |
| 9 (RLIN) | 10815 |
| 245 ## - TITLE STATEMENT | |
| Title | Inhaled sedation in the |
| Remainder of title | A new option and its technical prerequisites |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Homburg, Germany |
| Name of publisher, distributor, etc. | Springer Fachmedien Wiesbaden GmbH, part of Springer Nature |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 58 Pages |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Treatment of critically ill patients in the intensive care unit (ICU) is often<br/>associated with unpleasant perceptions, especially if artificial ventilation is<br/>interfering with natural breathing. To improve tolerance with the ventilator,<br/>patients are routinely sedated with intravenous drugs. These sedative drugs<br/>however have side effects, they accumulate in the body and this will slow<br/>down their elimination afterwards. They may also cause organ dysfunction<br/>and increase mortality.<br/>On the search for alternatives, volatile anaesthetics (VA), especially halothane, isoflurane and sevoflurane, had been used successfully since the nineteen<br/>fifties. Until recently, their use had however been limited because ICU ventilators are technically not designed for the application of VA and because<br/>there was limited experience with effects of their long term use in humans.<br/>Therefore we, the team of anaesthesiologists of the St. Josef-Hospital, RuhrUniversität Bochum, decided in the mid nineteen nineties to scientifically<br/>examine the use of VA in the ICU.<br/>At this time, gas scavenging was needed in order to be able to apply VA in<br/>the ICU setting. Luckily, we were able to convince the hospital administration of the Katholisches Klinikum Bochum to equip the newly built surgical<br/>ICU with such a gas scavenging system.<br/>After elimination of this first hurdle, we found Dr. Meiser to be an ideal candidate, enthusiastic enough to take things in his own hands despite all presumed but yet unknown difficulties of the practical realization.<br/>From the beginning, installing and performing inhaled sedation demanded<br/>quite some improvisation from all team members, as well as additional monitoring and surveillance leading to increased workload. With enthusiasm,<br/>Dr. Meiser took the challenge of sustained motivation of all team members,<br/>to adopt the new therapeutic option whenever possible and sensible, and over<br/>the years he gained a high recognition from staff.<br/>In the late nineteen nineties, the first studies started under his direction in our<br/>hospital, and in the early years of the third millennium the first randomized<br/>controlled trial on inhaled sedation with desflurane was published in a highly<br/>ranked journal. |
| Expansion of summary note | The introduction of the reflection principle for VA in 2004 simplified their<br/>application in the ICU setting, and further increased acceptance by staff. VA<br/>reflection on the one hand decreased consumption, and on the other hand it<br/>made preinstalled active gas scavenging systems dispensable.<br/>However, over the years, the technical realization of inhaled sedation seemed<br/>like a series of pitfalls and new technical challenges. Therefore, with the<br/>scientific cooperation of Professor Belda, Valencia, Spain, it was all the<br/>more fruitful, by distributing the load of unexpected problems using further<br/>scientific approaches.<br/>The research project was slowed down in 2010 due to Dr. Meiser moving<br/>from the St. Josef-Hospital Bochum to the University Hospital of the Saarland, Homburg, where the new method of inhaled sedation had to be introduced once more.<br/>It is all the more admirable, that Dr. Meiser and his teams were meeting all<br/>the new challenges and did not lose track of their goals. These goals may be<br/>summarized up to now: scientific proof that the use of VA in critically ill<br/>patients is not only economically viable but may also positively influence the<br/>clinical management of the patients and may improve organ function.<br/>On their way, Dr. Meiser and his teams have reached several interim goals,<br/>and further successful results are in sight. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| General subdivision | Intensive care unit |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | BOOKS |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 05/21/2021 | EBS3475 | 05/21/2021 | 05/21/2021 | BOOKS |