Anesthesia and Neurotoxicity
Yuji Morimoto
Anesthesia and Neurotoxicity - illustrated - Hokkaido University Graduate School of Medicine Sapporo Hokkaido Japan Springer 2017 - 167 pages
This book, written by leading Japanese experts in the field, describes the latest findings on the neurotoxicity of anesthetics for the developing brain, postoperative delirium and cognitive dysfunction.
It describes the risk factors for postoperative cognitive dysfunction in elderly surgical patients. Since the number of elderly patients undergoing surgery and anesthesia continues to increase, it is important to improve our understanding of the risks and mechanisms of postoperative delirium and cognitive dysfunction, potential ways to prevent or alleviate them and the public health implications.
Recently, it has been shown that using anesthetics on the developing brain causes apoptotic neurodegeneration and persistent learning/memory deficits later in life. Anesthesiologists need more information on this mechanism in the human brain.
The negative effects of anesthesia and surgery on the nervous system have attracted attention lately; this book provides physicians, researchers, and postdocs with invaluable information on this topic.
4431556249 9784431556244 = Anesth Analg anesthesia anesthesia exposure Anesthesiology anesthetic agents animals Ann Thorac Surg aortic apoptosis artery bypass grafting assessment associated BDNF behavior bypass graft surgery bypass surgery CAM-ICU cardiac surgery cardiopulmonary bypass caspase cell cerebral clinical cognitive decline cognitive function cognitive impairment cohort study colleagues coronary artery bypass cytokines decrease deficits delirium dementia desflurane developing brain development of POCD dexmedetomidine diagnosis disorder drugs effects elderly patients evaluation exposure to anesthesia GABAA receptors Geriatr hippocampus hypoactive incidence rate increase induced inflammation inflammatory inhibition isoflurane ketamine long-term major vascular surgery memory mg/kg mice microglia microglial activation neonatal neuroapoptosis neurocognitive neurodevelopmental neuroinflammation neuronal neuropsychological tests neurotoxicity NMDA NMDA receptors noncardiac surgery NT scores observed off-pump ONCAB OPCAB outcomes pathway patients undergoing POCD postoperative cognitive dysfunction postoperative delirium preoperative propofol rat brain rate of POCD reported risk factors rodents sevoflurane surgical symptoms synapse tion valvular surgery week Z-score
-- Medical › Anesthesiology -- Medical / Anesthesiology-- Medical / Clinical Medicine --Medical / Neurology-- Medical / Pharmacology
617.96 MOR
Anesthesia and Neurotoxicity - illustrated - Hokkaido University Graduate School of Medicine Sapporo Hokkaido Japan Springer 2017 - 167 pages
This book, written by leading Japanese experts in the field, describes the latest findings on the neurotoxicity of anesthetics for the developing brain, postoperative delirium and cognitive dysfunction.
It describes the risk factors for postoperative cognitive dysfunction in elderly surgical patients. Since the number of elderly patients undergoing surgery and anesthesia continues to increase, it is important to improve our understanding of the risks and mechanisms of postoperative delirium and cognitive dysfunction, potential ways to prevent or alleviate them and the public health implications.
Recently, it has been shown that using anesthetics on the developing brain causes apoptotic neurodegeneration and persistent learning/memory deficits later in life. Anesthesiologists need more information on this mechanism in the human brain.
The negative effects of anesthesia and surgery on the nervous system have attracted attention lately; this book provides physicians, researchers, and postdocs with invaluable information on this topic.
4431556249 9784431556244 = Anesth Analg anesthesia anesthesia exposure Anesthesiology anesthetic agents animals Ann Thorac Surg aortic apoptosis artery bypass grafting assessment associated BDNF behavior bypass graft surgery bypass surgery CAM-ICU cardiac surgery cardiopulmonary bypass caspase cell cerebral clinical cognitive decline cognitive function cognitive impairment cohort study colleagues coronary artery bypass cytokines decrease deficits delirium dementia desflurane developing brain development of POCD dexmedetomidine diagnosis disorder drugs effects elderly patients evaluation exposure to anesthesia GABAA receptors Geriatr hippocampus hypoactive incidence rate increase induced inflammation inflammatory inhibition isoflurane ketamine long-term major vascular surgery memory mg/kg mice microglia microglial activation neonatal neuroapoptosis neurocognitive neurodevelopmental neuroinflammation neuronal neuropsychological tests neurotoxicity NMDA NMDA receptors noncardiac surgery NT scores observed off-pump ONCAB OPCAB outcomes pathway patients undergoing POCD postoperative cognitive dysfunction postoperative delirium preoperative propofol rat brain rate of POCD reported risk factors rodents sevoflurane surgical symptoms synapse tion valvular surgery week Z-score
-- Medical › Anesthesiology -- Medical / Anesthesiology-- Medical / Clinical Medicine --Medical / Neurology-- Medical / Pharmacology
617.96 MOR