Atlas of Skeletal Muscle Pathology
J.R. Anderson
Atlas of Skeletal Muscle Pathology - illustrated - Boston Springer Science & Business Media 2012 - 168 pages - Volume 9 of Current Histopathology .
Contents:
Consultant editors note
General cellular reactions
Motor neuron disease
Spinal muscular atrophy SMA 45
Peripheral neuropathy
Muscular dystrophy
Other forms of muscular dystrophy
O Limb girdle and scapuloperoneal
Congenital myopathies
Inflammatory myopathy
Inflammatory myopathy
Metabolic myopathies
Druginduced myopathies
Endocrine myopathies
With the advent of enzyme histochemistry, which this field and simplistic theories will be expanded or revealed hitherto unseen pathological differences discarded. between muscle disorders, muscle biopsy assumed Diseased muscle cells, as any other cell type, show an important diagnostic role. The investigation is easily only limited morphological changes. However bizarre, performed and is being undertaken with increasing very few of these changes, if any, are pathognomonic of frequency. Nevertheless there is still a tendency to a single disease. The exact significance of microscopic regard its interpretation as highly specialized and out findings is to a large extent determined by their clinical side the province of the general histopathologist. In this context. Thus, although this is an atlas, it is definitely atlas I have tried to lift the veil of neuropathological not designed to promote 'spot' histological diagnoses. I mystique and to describe and illustrate the basic have aimed to provide a guide to pathological reactions reactions of muscle cells. of muscle which will be useful to the practising histo Interpretation of the biopsy depends not only upon pathologist and all students of neuro-muscular disease. recognition of morphological abnormalities, but upon I hope that recognition of the lack of specificity of understanding why they occur. Throughout the atlas I individual morphological features will encourage the have attempted to correlate morphological changes . close clinico-pathological correlation which is essential with pathogenetic mechanisms.
9400948662 9789400948662 = abnormalities adult ATP-ase pH 9.4 ATP-ase reaction atrophic fibres axon biopsy shows carnitine central core disease central nuclei childhood chronic SMA congenital fibre type congenital myopathy connective tissue cytoplasm Deltoid biopsy dermatomyositis diagnosis disorders distal Duchenne dystrophy Electron microscopy Ex 300 Figure Facioscapulohumeral fascicles fibre atrophy fibre type disproportion fibres Figures fibrosis glycogen H & Ex histochemical histological histology hyaline fibres hypertrophied fibres Inclusion body myositis innervation lesion Limb girdle syndrome lipid lysosomes membrane metabolic mild mitochondria motor neuron disease motor units muscle biopsy muscle cell muscle fibres muscular dystrophy myasthenia gravis myofibrils myosin myositis myotonic dystrophy NADH-TR necrosis necrotic fibres Nemaline myopathy nerve Neuro normal onset oxidative enzyme reaction pathological patients peripheral neuropathy polymyositis progressive proximal muscle weakness Quadriceps re-innervation Serial section shown in Figures skeletal muscle small fibres Small group atrophy spinal muscular atrophy staining steroid type 1 fibres type grouping usually vacuoles variation in fibre
--Muscular Diseases-pathologyatlases.-- Medical / Pathology-- Medical / Internal Medicine--Medical / Clinical Medicine-- Medical › Pathology
W1 CU788JBA v.9/WE 17 A5468al RC 925.5.A53 1985
616.7'407'58 AND
Atlas of Skeletal Muscle Pathology - illustrated - Boston Springer Science & Business Media 2012 - 168 pages - Volume 9 of Current Histopathology .
Contents:
Consultant editors note
General cellular reactions
Motor neuron disease
Spinal muscular atrophy SMA 45
Peripheral neuropathy
Muscular dystrophy
Other forms of muscular dystrophy
O Limb girdle and scapuloperoneal
Congenital myopathies
Inflammatory myopathy
Inflammatory myopathy
Metabolic myopathies
Druginduced myopathies
Endocrine myopathies
With the advent of enzyme histochemistry, which this field and simplistic theories will be expanded or revealed hitherto unseen pathological differences discarded. between muscle disorders, muscle biopsy assumed Diseased muscle cells, as any other cell type, show an important diagnostic role. The investigation is easily only limited morphological changes. However bizarre, performed and is being undertaken with increasing very few of these changes, if any, are pathognomonic of frequency. Nevertheless there is still a tendency to a single disease. The exact significance of microscopic regard its interpretation as highly specialized and out findings is to a large extent determined by their clinical side the province of the general histopathologist. In this context. Thus, although this is an atlas, it is definitely atlas I have tried to lift the veil of neuropathological not designed to promote 'spot' histological diagnoses. I mystique and to describe and illustrate the basic have aimed to provide a guide to pathological reactions reactions of muscle cells. of muscle which will be useful to the practising histo Interpretation of the biopsy depends not only upon pathologist and all students of neuro-muscular disease. recognition of morphological abnormalities, but upon I hope that recognition of the lack of specificity of understanding why they occur. Throughout the atlas I individual morphological features will encourage the have attempted to correlate morphological changes . close clinico-pathological correlation which is essential with pathogenetic mechanisms.
9400948662 9789400948662 = abnormalities adult ATP-ase pH 9.4 ATP-ase reaction atrophic fibres axon biopsy shows carnitine central core disease central nuclei childhood chronic SMA congenital fibre type congenital myopathy connective tissue cytoplasm Deltoid biopsy dermatomyositis diagnosis disorders distal Duchenne dystrophy Electron microscopy Ex 300 Figure Facioscapulohumeral fascicles fibre atrophy fibre type disproportion fibres Figures fibrosis glycogen H & Ex histochemical histological histology hyaline fibres hypertrophied fibres Inclusion body myositis innervation lesion Limb girdle syndrome lipid lysosomes membrane metabolic mild mitochondria motor neuron disease motor units muscle biopsy muscle cell muscle fibres muscular dystrophy myasthenia gravis myofibrils myosin myositis myotonic dystrophy NADH-TR necrosis necrotic fibres Nemaline myopathy nerve Neuro normal onset oxidative enzyme reaction pathological patients peripheral neuropathy polymyositis progressive proximal muscle weakness Quadriceps re-innervation Serial section shown in Figures skeletal muscle small fibres Small group atrophy spinal muscular atrophy staining steroid type 1 fibres type grouping usually vacuoles variation in fibre
--Muscular Diseases-pathologyatlases.-- Medical / Pathology-- Medical / Internal Medicine--Medical / Clinical Medicine-- Medical › Pathology
W1 CU788JBA v.9/WE 17 A5468al RC 925.5.A53 1985
616.7'407'58 AND