A Report on Clinical and Cytological Patterns of Patients Presenting With Lymphadenopathy in Mwanza, Tanzania.
Glorian Goodluck Nnko CUHAS/MD/4002487/T/18
A Report on Clinical and Cytological Patterns of Patients Presenting With Lymphadenopathy in Mwanza, Tanzania. - Mwanza, Tanzania: Catholic University of Health and Allied Sciences [CUHAS – Bugando] : ©2023 - 34 Pages Includes References and Appendicies
Abstract:
Introduction: Lymphadenopathy stands as a prevalent clinical manifestation among patients, with a range of underlying causes spanning from inflammatory to malignant conditions. FNAC is increasingly being ap¬plied to Lymphnode lesions as it permits rapid diagnosis with minimal intervention. The knowledge of the pattern of lymphadenopathy in a given geographical region is essential for making a confident diagnosis or suspecting a disease
Objective: To determine the clinical and cytological patterns of patients presenting with lymphadenopathy in Mwanza.
Methodology: A cross-section hospital-based study was conducted in the outpatient clinics at Bugando Medical Centre and Sekoture Regional Referral hospitals whereby all patients with lymphadenopathy with palpable lymph node(s) above 1cm were involved in the study.
Results: A total of 207 patients were enrolled in this study, with a predominance of females over males. The distribution showed that 61.8% of the participants were females, while males constituted 38.2%, resulting in a male-to-female ratio of 1:1.6. Participants' ages ranged from 0 to 80 years, with an average age of 36.52 ± 15.8 years. Interestingly, there were comparable mean ages observed for both males and females. The age group most significantly impacted overall was 21 to 30 years. Majority of our participants were HIV negative (69%) and those positive (11%) were on ART of which most of them were on TLD regimen. Fever was the predominant symptom observed in most patients, accounting for 155 out of 207 cases, and of all palpable lymph nodes, the cervical region exhibited the highest prevalence. A significant majority of our diagnoses (75.1%) were attributed to reactive lymphadenopathy, with inadequate smears accounting for 7.5% of cases. Tuberculosis constituted 7.4% of the total patient population.
Conclusion: Fine needle aspiration cytology (FNAC) emerges as a valuable tool for swift and safe diagnosis, aiding treatment decisions. Furthermore, our investigation into demographic variations reveals a higher occurrence in females, consistent with previous studies, and diverse age-related presentations. The study contributes to an improved understanding of lymphadenopathy, empowering doctors to enhance patient care through informed decisions.
Phone: +255 28 298 3384 Fax: +255 28 298 3386 Email: vc@bugando.ac.tz Website: www.bugando.ac.tz
--Pathology --Hematology
A Report on Clinical and Cytological Patterns of Patients Presenting With Lymphadenopathy in Mwanza, Tanzania. - Mwanza, Tanzania: Catholic University of Health and Allied Sciences [CUHAS – Bugando] : ©2023 - 34 Pages Includes References and Appendicies
Abstract:
Introduction: Lymphadenopathy stands as a prevalent clinical manifestation among patients, with a range of underlying causes spanning from inflammatory to malignant conditions. FNAC is increasingly being ap¬plied to Lymphnode lesions as it permits rapid diagnosis with minimal intervention. The knowledge of the pattern of lymphadenopathy in a given geographical region is essential for making a confident diagnosis or suspecting a disease
Objective: To determine the clinical and cytological patterns of patients presenting with lymphadenopathy in Mwanza.
Methodology: A cross-section hospital-based study was conducted in the outpatient clinics at Bugando Medical Centre and Sekoture Regional Referral hospitals whereby all patients with lymphadenopathy with palpable lymph node(s) above 1cm were involved in the study.
Results: A total of 207 patients were enrolled in this study, with a predominance of females over males. The distribution showed that 61.8% of the participants were females, while males constituted 38.2%, resulting in a male-to-female ratio of 1:1.6. Participants' ages ranged from 0 to 80 years, with an average age of 36.52 ± 15.8 years. Interestingly, there were comparable mean ages observed for both males and females. The age group most significantly impacted overall was 21 to 30 years. Majority of our participants were HIV negative (69%) and those positive (11%) were on ART of which most of them were on TLD regimen. Fever was the predominant symptom observed in most patients, accounting for 155 out of 207 cases, and of all palpable lymph nodes, the cervical region exhibited the highest prevalence. A significant majority of our diagnoses (75.1%) were attributed to reactive lymphadenopathy, with inadequate smears accounting for 7.5% of cases. Tuberculosis constituted 7.4% of the total patient population.
Conclusion: Fine needle aspiration cytology (FNAC) emerges as a valuable tool for swift and safe diagnosis, aiding treatment decisions. Furthermore, our investigation into demographic variations reveals a higher occurrence in females, consistent with previous studies, and diverse age-related presentations. The study contributes to an improved understanding of lymphadenopathy, empowering doctors to enhance patient care through informed decisions.
Phone: +255 28 298 3384 Fax: +255 28 298 3386 Email: vc@bugando.ac.tz Website: www.bugando.ac.tz
--Pathology --Hematology