Prevalence of Hepatitis B Surface Antigens and Associated Factors among Pregnant Women Attending To Antenatal Care Clinics in Unguja, Zanzibar
Anodi Denis Mhoza CUHAS/BM/1001055/T/20
Prevalence of Hepatitis B Surface Antigens and Associated Factors among Pregnant Women Attending To Antenatal Care Clinics in Unguja, Zanzibar - Mwanza, Tanzania: Catholic University of Health and Allied Sciences [CUHAS – Bugando] : ©2023 - 57 Pages Includes References and Appendicies
Abstract:
Introduction: Hepatitis B virus (HBV) infection is an infection of the liver that accounts for up to 80% of all cases of hepatocellular carcinoma worldwide. As of 2019, there were 354 million people worldwide infected with hepatitis B, of which 257 million were chronically infected. In Tanzania the prevalence ranges from 0.4%-11.8%. However, previous there was limited data on the magnitude of HBV among pregnant women attending different antenatal clinics in Unguja, Zanzibar hindering its control efforts. Therefore, this study determined the prevalence of Hepatitis B surface antigens (HBsAg) and associated factors among pregnant women attending to antenatal care clinics in Unguja, Zanzibar.
Methodology: A hospital based cross sectional study involved 270 pregnant women attending to antenatal care clinics in Unguja, Zanzibar, conducted between May and July 2023. Data was collected using pretested structured data collection tool. Detection of hepatitis B surface antigen (HBsAg) was done by using immunochromatographic test. Obtained data analyzed by using STATA version 15.
Results: The Mean (±SD) age of participants was 26.9(±5.7) years, majority of them were married 245(90.7%) and from urban 236(87.41%). The prevalence of HBsAg positivity among the pregnant women was 2.96% (8/270) [95% CI: 1.5%-5.2%]. Being HIV positivity (OR: 22, 95% CI: 2.7- 190.5, P=0.001), history of syphilis (OR: 12, 95% CI: 1.05- 156.2, P=0.046) were significant associated with HBsAg positivity
Conclusion: Active hepatitis B infection among pregnant women in Unguja-Zanzibar is low according to WHO classification of hepatitis B infection severity and associated with HIV positivity and syphilis disease. Despite low prevalence of hepatitis B infection routine screening of HBsAg coupled with the vaccination of those at risk should be improved to prevent hepatitis B infection complications.
Phone: +255 28 298 3384 Fax: +255 28 298 3386 Email: vc@bugando.ac.tz Website: www.bugando.ac.tz
--Medical Laboratory Sciences --Microbiology & Immunology
Prevalence of Hepatitis B Surface Antigens and Associated Factors among Pregnant Women Attending To Antenatal Care Clinics in Unguja, Zanzibar - Mwanza, Tanzania: Catholic University of Health and Allied Sciences [CUHAS – Bugando] : ©2023 - 57 Pages Includes References and Appendicies
Abstract:
Introduction: Hepatitis B virus (HBV) infection is an infection of the liver that accounts for up to 80% of all cases of hepatocellular carcinoma worldwide. As of 2019, there were 354 million people worldwide infected with hepatitis B, of which 257 million were chronically infected. In Tanzania the prevalence ranges from 0.4%-11.8%. However, previous there was limited data on the magnitude of HBV among pregnant women attending different antenatal clinics in Unguja, Zanzibar hindering its control efforts. Therefore, this study determined the prevalence of Hepatitis B surface antigens (HBsAg) and associated factors among pregnant women attending to antenatal care clinics in Unguja, Zanzibar.
Methodology: A hospital based cross sectional study involved 270 pregnant women attending to antenatal care clinics in Unguja, Zanzibar, conducted between May and July 2023. Data was collected using pretested structured data collection tool. Detection of hepatitis B surface antigen (HBsAg) was done by using immunochromatographic test. Obtained data analyzed by using STATA version 15.
Results: The Mean (±SD) age of participants was 26.9(±5.7) years, majority of them were married 245(90.7%) and from urban 236(87.41%). The prevalence of HBsAg positivity among the pregnant women was 2.96% (8/270) [95% CI: 1.5%-5.2%]. Being HIV positivity (OR: 22, 95% CI: 2.7- 190.5, P=0.001), history of syphilis (OR: 12, 95% CI: 1.05- 156.2, P=0.046) were significant associated with HBsAg positivity
Conclusion: Active hepatitis B infection among pregnant women in Unguja-Zanzibar is low according to WHO classification of hepatitis B infection severity and associated with HIV positivity and syphilis disease. Despite low prevalence of hepatitis B infection routine screening of HBsAg coupled with the vaccination of those at risk should be improved to prevent hepatitis B infection complications.
Phone: +255 28 298 3384 Fax: +255 28 298 3386 Email: vc@bugando.ac.tz Website: www.bugando.ac.tz
--Medical Laboratory Sciences --Microbiology & Immunology