Patterns of Pathogenics Bacteria Causing Urinary Tract Infections Among Patients in District Hospitals in Mwanza, Tanzania.
Yodosi, Ritha CUHAS/BM/1000294/T/16
Patterns of Pathogenics Bacteria Causing Urinary Tract Infections Among Patients in District Hospitals in Mwanza, Tanzania. - Mwanza, Tanzania : Catholic University of Health and Allied Sciences [CUHAS - Bugando] : ©16.09.2019 - viii; 33 Pages Includes References and Appendices
Abstract:
Background: Pyelonephritis, kidney stones and urosepsis are some of the complications of urinary tract infections (UTI), increasing rates of morbidity and mortality to this common disease across the world. The descriptions of patterns, pathogens, risk factors and antimicrobial resistance profiles for UTI is well described in tertiary and some regional hospitals across the country. This study aims at determining patterns of pathogenic bacteria causing UTI among patients in various district hospitals in Mwanza, Tanzania.
Methods: This cross sectional analytical study was conducted among 256 patients in various district hospitals in Mwanza-Tanzania. Pre-tested data collection tool was to collect information from study participants. Urine specimen were collected in sterile containers and then transported to Microbiology laboratory within 2 hours of collection for processing adhering to standard operating procedures (SOPs). Data was cleaned, coded using Microsoft excel spreadsheet and analyzed using STATA (StataCorp LLC, USA) version 13.
Results: A total of 256 participant were enrolled, their medium age was 23 (IQR: 5-37) years, and about two third 158 (61.7%) were female. The prevalence of UTI among was 27.7% (71/256), with the proportions in Magu, Misungwi and Sumve being 43.7%, 40.8% and 15.5%, respectively. The most common bacteria were E. coli 24/78 (30.8%) followed by S. aureus 19/78 (24.4%). The proportion of ESBL production among Gram negative bacteria was 7.0% (4/57). UTI was significantly higher among female than male (23.3% versus 20.4%; p-value=0.039). Moreover, health facility, neighbor domestic animals, history of fever and use of invasive devices were found to be statistically significantly related with UTI (p-values of <0.001, 0.034, 0.004 and 0.019 respectively).
Conclusions: The prevalence of UTI from the patients attending district hospitals (21.7%) was comparable to previous studies within Tanzania, and Escherichia coli and Staphylococcus aureus were found to be the most common uropathogens. Identified risk factors should be used for priority screening of patients and for targeted preventive measures.
Significance: This study was expanding ongoing efforts on creating evidence based management of patients with UTI in tertiary and regional hospitals to district hospitals, so as to have comprehensive interventional measures.
Phone: +255 28 298 3384 Fax: +255 28 298 3386 Email: vc@bugando.ac.tz Website: www.bugando.ac.tz
--Medical Laboratory Sciences --Microbiology and Immunology
Patterns of Pathogenics Bacteria Causing Urinary Tract Infections Among Patients in District Hospitals in Mwanza, Tanzania. - Mwanza, Tanzania : Catholic University of Health and Allied Sciences [CUHAS - Bugando] : ©16.09.2019 - viii; 33 Pages Includes References and Appendices
Abstract:
Background: Pyelonephritis, kidney stones and urosepsis are some of the complications of urinary tract infections (UTI), increasing rates of morbidity and mortality to this common disease across the world. The descriptions of patterns, pathogens, risk factors and antimicrobial resistance profiles for UTI is well described in tertiary and some regional hospitals across the country. This study aims at determining patterns of pathogenic bacteria causing UTI among patients in various district hospitals in Mwanza, Tanzania.
Methods: This cross sectional analytical study was conducted among 256 patients in various district hospitals in Mwanza-Tanzania. Pre-tested data collection tool was to collect information from study participants. Urine specimen were collected in sterile containers and then transported to Microbiology laboratory within 2 hours of collection for processing adhering to standard operating procedures (SOPs). Data was cleaned, coded using Microsoft excel spreadsheet and analyzed using STATA (StataCorp LLC, USA) version 13.
Results: A total of 256 participant were enrolled, their medium age was 23 (IQR: 5-37) years, and about two third 158 (61.7%) were female. The prevalence of UTI among was 27.7% (71/256), with the proportions in Magu, Misungwi and Sumve being 43.7%, 40.8% and 15.5%, respectively. The most common bacteria were E. coli 24/78 (30.8%) followed by S. aureus 19/78 (24.4%). The proportion of ESBL production among Gram negative bacteria was 7.0% (4/57). UTI was significantly higher among female than male (23.3% versus 20.4%; p-value=0.039). Moreover, health facility, neighbor domestic animals, history of fever and use of invasive devices were found to be statistically significantly related with UTI (p-values of <0.001, 0.034, 0.004 and 0.019 respectively).
Conclusions: The prevalence of UTI from the patients attending district hospitals (21.7%) was comparable to previous studies within Tanzania, and Escherichia coli and Staphylococcus aureus were found to be the most common uropathogens. Identified risk factors should be used for priority screening of patients and for targeted preventive measures.
Significance: This study was expanding ongoing efforts on creating evidence based management of patients with UTI in tertiary and regional hospitals to district hospitals, so as to have comprehensive interventional measures.
Phone: +255 28 298 3384 Fax: +255 28 298 3386 Email: vc@bugando.ac.tz Website: www.bugando.ac.tz
--Medical Laboratory Sciences --Microbiology and Immunology