Prevalence, Intensity of Infection and Factors Associated with Schistosoma Mansoni Infection Among Children Attending Antiretroviral Treatment Clinic at Nyanguge Health Centre in Magu District, Northern Western Tanzania.
Shikabwe, Msafiri CUHAS/BM/1000207/T/15
Prevalence, Intensity of Infection and Factors Associated with Schistosoma Mansoni Infection Among Children Attending Antiretroviral Treatment Clinic at Nyanguge Health Centre in Magu District, Northern Western Tanzania. - Mwanza, Tanzania: Catholic University of Health and Allied Sciences [CUHAS – Bugando] : ©2018 - 43 Pages Includes References
Abstract:
Introduction: S. mansoni and Human Immune Deficiency virus (HIV/AIDS) co infection is usually common in Sub Saharan Africa, Schistosomiasis is among neglected tropical diseases (NTD) affecting different populations including children during their routine activities especially playing habit with fresh water contaminated with S. mansoni. Despite of the problem there are limited data concerning co infection with S. mansoni and AIDS among children on antiretroviral treatment.
Objective: This study aimed to determine prevalence, intensity of infection and factors associated with Schistosoma mansoni among children attending CTC clinic at Nyanguge health centre in Magu district.
Method: Analytical cross-sectional study was conducted between June and July 2018 which include 134 children age between 1 to 16 years. Single stool samples was collected from all eligible participants and screened for Schistosoma mansoni by using Kato Katz technique to determine intensity and urine for circulating cathodic antigen (CCA) for determination of prevalence, questionnaire was used for assessment of factors associated with Schistosoma infection.
Results: Majority of parents/guardians 88.4% (n=99/112) attained primary school education 15.6% (n=13/112). 46.4% (n=52) of children reported to have history of water contact when swimming/recreation and fetching water for domestic use. The source of water were open wells 54.5% (n=61), tape water 29.5% (n=33) and lake 15.2% (n=17), also 59.8% (n=67) reported to receive anthelminthic drug while 40.2% (n=45) had no history of taking anthelminthic. Of all children 88/112 (78.6%) of had CD4 results at the initiation of treatment and 24 (21.4%) had no CD4 results, only 69/112 (61.6%) children were checked for CD4 count on second year and only 30/112 (26.8%) children had their CD4 count checked on the third year. Based on CCA test, 28.8% (n=32/112) of the children has S. mansoni infection. There was no age (x² = 0.0295, p=0.86) and sex x² =1.7403, p=0.019) difference. However, children with history of water contacts had higher prevalence of Schistosomiasis (x²= 12.1715, p<0.001). Based on Kato Katz technique, 10.68% (n=11/103 of the children had detectable Schistosoma mansoni egg in their stool samples. The geometric mean egg per gram of feaces was 13.49 gmepg (95% CI: 30.83-175.24)
Conclusion and recommendations: This study high prevalence of Schistosoma mansoni among children attending CTC clinic at Nyanguge health centre (28.8%). Routine antiworming is required for this group of children and health education to the community on prevention and control of Schistosomiasis and importance of CD4 testing among this group of children.
Wurzburg Road 35, BMC Premises, Post Code: 33102: P. O. Box 1464, Mwanza – Tanzania: Phone: +255 28 298 3384: Fax: +255 28 298 3386: Email: vc@bugando.ac.tz : www.bugando.ac.tz
--Medical Laboratory Sciences--Parasitology and Entomology
Prevalence, Intensity of Infection and Factors Associated with Schistosoma Mansoni Infection Among Children Attending Antiretroviral Treatment Clinic at Nyanguge Health Centre in Magu District, Northern Western Tanzania. - Mwanza, Tanzania: Catholic University of Health and Allied Sciences [CUHAS – Bugando] : ©2018 - 43 Pages Includes References
Abstract:
Introduction: S. mansoni and Human Immune Deficiency virus (HIV/AIDS) co infection is usually common in Sub Saharan Africa, Schistosomiasis is among neglected tropical diseases (NTD) affecting different populations including children during their routine activities especially playing habit with fresh water contaminated with S. mansoni. Despite of the problem there are limited data concerning co infection with S. mansoni and AIDS among children on antiretroviral treatment.
Objective: This study aimed to determine prevalence, intensity of infection and factors associated with Schistosoma mansoni among children attending CTC clinic at Nyanguge health centre in Magu district.
Method: Analytical cross-sectional study was conducted between June and July 2018 which include 134 children age between 1 to 16 years. Single stool samples was collected from all eligible participants and screened for Schistosoma mansoni by using Kato Katz technique to determine intensity and urine for circulating cathodic antigen (CCA) for determination of prevalence, questionnaire was used for assessment of factors associated with Schistosoma infection.
Results: Majority of parents/guardians 88.4% (n=99/112) attained primary school education 15.6% (n=13/112). 46.4% (n=52) of children reported to have history of water contact when swimming/recreation and fetching water for domestic use. The source of water were open wells 54.5% (n=61), tape water 29.5% (n=33) and lake 15.2% (n=17), also 59.8% (n=67) reported to receive anthelminthic drug while 40.2% (n=45) had no history of taking anthelminthic. Of all children 88/112 (78.6%) of had CD4 results at the initiation of treatment and 24 (21.4%) had no CD4 results, only 69/112 (61.6%) children were checked for CD4 count on second year and only 30/112 (26.8%) children had their CD4 count checked on the third year. Based on CCA test, 28.8% (n=32/112) of the children has S. mansoni infection. There was no age (x² = 0.0295, p=0.86) and sex x² =1.7403, p=0.019) difference. However, children with history of water contacts had higher prevalence of Schistosomiasis (x²= 12.1715, p<0.001). Based on Kato Katz technique, 10.68% (n=11/103 of the children had detectable Schistosoma mansoni egg in their stool samples. The geometric mean egg per gram of feaces was 13.49 gmepg (95% CI: 30.83-175.24)
Conclusion and recommendations: This study high prevalence of Schistosoma mansoni among children attending CTC clinic at Nyanguge health centre (28.8%). Routine antiworming is required for this group of children and health education to the community on prevention and control of Schistosomiasis and importance of CD4 testing among this group of children.
Wurzburg Road 35, BMC Premises, Post Code: 33102: P. O. Box 1464, Mwanza – Tanzania: Phone: +255 28 298 3384: Fax: +255 28 298 3386: Email: vc@bugando.ac.tz : www.bugando.ac.tz
--Medical Laboratory Sciences--Parasitology and Entomology